Monkeypox virus - Colorised transmission electron micrograph of monkeypox particles (teal) found within an infected cell (brown), cultured in the laboratory. Source: NIAID on Flickr (CC BY 2.0)
Monkeypox virus - Colorised transmission electron micrograph of monkeypox particles (teal) found within an infected cell ( brown ), cultured in the laboratory. Source: NIAID on Flickr (CC BY 2. Monkeypox can sometimes lead to neurological complications such as encephalitis (brain inflammation), confusion or seizures, finds a new review of evidence led by a UCL researcher. Several studies incorporated in the systematic review and meta-analysis of evidence, published in eClinicalMedicine , also found that muscle aches, fatigue, headache, anxiety and depression were all relatively common among monkeypox patients. Across the studies with relevant evidence, 2-3% of patients had severe complications such as seizure or encephalitis, although those studies mainly involved hospitalised patients from previous years. The researchers say there is not yet enough evidence to estimate neurological complication prevalence in the current outbreak. The team led by researchers at UCL, Barts Health NHS Trust, Guy's and St Thomas' NHS Foundation Trust, and King's College London, looked for any studies reporting neurological or psychiatric symptoms of monkeypox that had been reported up until May 2022, before the outbreak spread globally.
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