Prazosin prevents memory decline in mouse model of Alzheimer’s disease, a study has found.
Adapted from a news release from Alzheimer's Research UK Scientists at Imperial College London have found that the drug prazosin, used to treat high blood pressure, may have potential benefits in Alzheimer's. The study found that the drug could prevent memory loss in mice showing characteristic features of the disease. The work was funded by Alzheimer's Research UK , Fundació Marató TV3 , and Alzheimer's Society in partnership with the Bupa Foundation. The research is published this month in the journal Neurobiology of Aging . Fast and effective communication between brain cells is essential for the normal functioning of the brain and is orchestrated by chemical messengers called neurotransmitters. The neurotransmitter noradrenaline, as well as several others, can become disrupted in particular areas of the brain during Alzheimer's. Although best known for stimulating the brain in times of stress, noradrenaline has a range of functions in the brain, including roles in memory, inflammation and the immune system.
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