Cancer cells
Researchers at King's have achieved a breakthrough in understanding a biological process which causes many common cancers, including lung and breast cancer. The achievement opens up new possibilities for the development of improved cancer drugs. The findings are published in the journal Molecular and Cellular Biology. Working with the Science and Technology Facilities Council (STFC) Central Laser Facility (CLF) and Computational Science and Engineering Department (CSED), the team solved a puzzle that has confounded scientists for more than 30 years. The researchers have discovered a previously unknown molecular shape which is partly responsible for transmitting the signals that instruct cells within the body when to grow and divide. It is the uncontrolled growth of cells that causes cancer to spread through the body. Until now, not enough was known about how these molecules, known as epidermal growth factor receptors (EGFRs), transmit messages in the development of cancer.
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