Brain cells' weakest links

People with degenerative neurological conditions could benefit from research that shows why their brain cells stop communicating properly. Scientists believe that the findings could help to develop treatments that slow the progress of a broad range of brain disorders such as Huntingdon's, Alzheimer's and Parkinson's diseases. The team at the University, led by Professor Tom Gillingwater, analysed how connection points between brain cells break down during disease and identified six proteins that control the process. Sending signals. When connection points in the brain, known as synapses, stop working - because of injury or disease - the chain of brain signalling breaks down and cannot be repaired. The research from The Roslin Institute and Centre for Integrative Physiology at the University will help scientists identify drugs that target these proteins. This could eventually enable clinicians to slow the progress of these disorders.