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Life Sciences - Health - 01.12.2022
Early life experiences can have long-lasting impact on genes
Early life experiences can have long-lasting impact on genes
Early life experiences can impact the activity of our genes much later on and even affect longevity, finds a new study in fruit flies led by UCL researchers. In the study published in Nature Aging , the scientists report that gene expression 'memory' can persist across the lifespan, and may present a novel target for improving late-life health.

Health - Life Sciences - 01.12.2022
Anti-ageing drug rapamycin might only benefit females
Anti-ageing drug rapamycin might only benefit females
The anti-ageing drug rapamycin only prolongs the lifespan of female fruit flies, but not that of males, finds a new study co-led by UCL researchers. Working with researchers from the Max Planck Institute for Biology of Ageing in Cologne, the team reports in Nature Aging that in addition, rapamycin only slowed the development of age-related pathological changes in the gut in female flies.

Environment - Life Sciences - 29.11.2022
Dormant microbes can ’switch on’ to cope with climate change
Dormant strains of bacteria that have previously adapted to cope with certain temperatures are switched back on during climatic change, study shows. The results, led by a team at Imperial College London and published today in eLife , have important implications for predicting the impact of global warming on ecosystems.

Environment - Life Sciences - 29.11.2022
New study suggests climate change may be affecting animal body size
New study suggests climate change may be affecting animal body size
A new study finds treeshrews increase in size in warmer settings, contrary to established norms. Our study is the first to demonstrate a rule reversal over time in any species. We need to revisit some of our assumptions about size variation as our climate continues to rapidly change. Maya Juman New evidence shows that some mammals increase in size in warmer settings, upsetting established norms and suggesting that climate change may be having an unexpected impact on animal body size.

Life Sciences - Health - 29.11.2022
Ancient viruses may hold key to effective gene therapy treatments
Scientists have unlocked key insights into virus evolution, revealing new information that could help develop treatments for a wide variety of genetic diseases. The research, which was led by scientists at the MRC-University of Glasgow Centre for Virus Research (CVR) and University of Massachusetts Chan Medical School, focuses on a group of small, ubiquitous viruses called 'parvoviruses' (from the Latin word "parvus" meaning 'small', 'puny' or 'unimportant').

Life Sciences - Environment - 28.11.2022
Live fast, avoid extinction: fast-lived species more resilient to human influences
Live fast, avoid extinction: fast-lived species more resilient to human influences
Animals that live fast - that is, frequent or abundant reproduction and short lifespans - are more resilient to human-driven land use changes than those with slow life-histories, finds a new study led by UCL researchers. Across the globe, in areas that have experienced rapid expansion of cropland or bare soil, fast-lived species have increased in numbers in recent decades while slow-lived species are in decline, according to the findings published in Global Change Biology .

Environment - Life Sciences - 28.11.2022
Mussel survey reveals alarming degradation of River Thames ecosystem since the 1960s
Mussel survey reveals alarming degradation of River Thames ecosystem since the 1960s
Scientists replicated a 1964 River Thames survey and found that mussel numbers have declined by almost 95%, with one species - the depressed river mussel - completely gone. This dramatic decline in native mussel populations is very worrying, and we are not sure what's driving it David Aldridge The detailed study measured the change in size and number of all species of mussel in a stretch of the River Thames near Reading between 1964 and 2020.

Health - Life Sciences - 21.11.2022
Hospitals more risky than farms when it comes to Klebsiella superbug spread, says study
Hospitals more risky than farms when it comes to Klebsiella superbug spread, says study
A study led by Bath's Milner Centre for Evolution investigated spread of Klebsiella bacteria between humans and the environment. An international team of scientists investigating transmission of a deadly drug resistant bacteria that rivals MRSA, has found that whilst the bugs are found in livestock, pets and the wider environment, they are rarely transmitted to humans through this route.

Health - Life Sciences - 21.11.2022
New Alzheimer’s genes discovered in world’s largest study
Two new genes that raise a person's risk of developing Alzheimer's Disease have been discovered by researchers. An international team, involving Cardiff University's Dementia Research Institute, compared 32,000 genetic codes from patients with Alzheimer's disease and healthy individuals. The research uncovered several new genes and specific mutations in those genes that lead to the development of Alzheimer's disease.

Life Sciences - Health - 18.11.2022
Lab grown 'mini eyes' help understanding of blindness in rare genetic condition
Lab grown ’mini eyes’ help understanding of blindness in rare genetic condition
Researchers at UCL have grown 'mini eyes', which make it possible to study and better understand the development of blindness in Usher syndrome for the first time. The 3D 'mini eyes', known as organoids, were grown from stem cells generated from skin samples donated by patients at Great Ormond Street Hospital for Children (GOSH).

Life Sciences - 17.11.2022
Education increases genetic risk of shortsightedness
Scientists have uncovered five genetic variants that increase a person's risk of becoming shortsighted the longer they stay in school. The research, led by Professor Jeremy Guggenheim of the University's School of Optometry and Vision Sciences, used genetic and health data from more than 340,000 participants with European ancestry.

Health - Life Sciences - 16.11.2022
Synthetic biology meets medicine: ’programmable molecular scissors’ could help fight COVID-19 infection
Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus, an approach that could be used to develop a new generation of antiviral drugs. XNAzymes are molecular scissors which recognise a particular sequence in the RNA, then chop it up Alex Taylor Enzymes are naturally occurring biological catalysts, which enable the chemical transformations required for our bodies to function - from translating the genetic code into proteins, right through to digesting food.

Life Sciences - 15.11.2022
Scientists grow concerned for the genetic health of otters in the UK
Long-term study reveals otter populations haven't reconnected genetically, despite strong recovery in population size. The genetic health of otters in Britain could be putting them at risk despite conservation efforts, according to a long-term study by Cardiff University's Otter Project. Studying data across two decades, the team has mapped for the first time the changing pattern of otter genetics.

Life Sciences - Health - 15.11.2022
Slow-moving shell of water can make Parkinson’s proteins ’stickier’
Water - which makes up the majority of every cell in the body - plays a key role in how proteins, including those associated with Parkinson's disease, fold, misfold, or clump together, according to a new study. The failure to look at the whole cellular environment has been limiting the field, which may be why we haven-t yet got an effective treatment for Parkinson's disease Gabriele Kaminski Schierle When attempting to discover potential treatments for protein misfolding diseases, researchers have primarily focused on the structure of the proteins themselves.

Life Sciences - 15.11.2022
Nerve cell discovery may lead to better treatment for diseases of the nervous system
Nerve cell discovery may lead to better treatment for diseases of the nervous system
A discovery that may improve treatment options for patients with neurodegenerative diseases has been made by scientists at Bath and KCL. A discovery that may improve treatment options for patients with neurodegenerative diseases has been made by scientists at King's College London and the University of Bath.

Health - Life Sciences - 15.11.2022
New RVC research identifies changing epidemiology of harmful foetal disease
A new study from the Royal Veterinary College (RVC) highlights the changing epidemiology of congenital toxoplasmosis (CT), a foetal disease which affects approximately 190,000 pregnancies around the world each year, and the need for more extensive research to understand the underlying causes responsible for these changes.

Health - Life Sciences - 15.11.2022
Hope for drug treatment to slow neurodegenerative disease
New research provides hope for drug treatment to slow neurodegenerative disease Scientists have found a new drug treatment that can slow the progression of neurodegenerative disease in mice. The breakthrough research may offer fresh hope in tackling currently untreatable conditions such as Alzheimer's disease.

Health - Life Sciences - 14.11.2022
Key cause of type 2 diabetes uncovered
Oxford Research reveals high blood glucose reprograms the metabolism of pancreatic beta-cells in diabetes. Glucose metabolites (chemicals produced when glucose is broken down by cells), rather than glucose itself, have been discovered to be key to the progression of type 2 diabetes.áIn diabetes, the pancreatic beta-cells do not release enough of the hormone insulin, which lowers blood glucose levels.

Health - Life Sciences - 11.11.2022
Scientists uncover potential 'electrical language' of breast cancer cells
Scientists uncover potential ’electrical language’ of breast cancer cells
New research has found variable voltages in the membranes of breast cancer cells, revealing clues about how they grow and spread. The research, led by Imperial College London and The Institute of Cancer Research, London , could help us better understand how cancer cells 'decide' when to multiply and where to spread to.

Life Sciences - Environment - 11.11.2022
The water flow rate of a fish’s ’home’ affects the survival of their offspring
The water flow where adult fish live can affect the body shape and survival of their offspring, according to new research. The study - led by an international collaboration between CRIOBE and the University of Glasgow, and published today in Functional Ecology - found that the survival of fish born from parents living under high water flow was reduced by half compared to fish born from those living under low water flow.
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