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Pharmacology
Results 51 - 100 of 654.
Trial aims to improve treatment for newborns with life-threatening sepsis
An international clinical trial co-led by UCL researchers will evaluate much-needed new antibiotic combinations for newborn babies with sepsis.
An international clinical trial co-led by UCL researchers will evaluate much-needed new antibiotic combinations for newborn babies with sepsis.
Boost for cancer patients as Clinical Trials Unit receives millions
The search for new cancer treatments in Southampton has been given a multi-million-pound boost providing hope for people diagnosed with the disease.
The search for new cancer treatments in Southampton has been given a multi-million-pound boost providing hope for people diagnosed with the disease.
First experts move into new world-class cancer research facility
World-leading scientists, clinicians and operational staff are now moving into a new £150m cancer research centre at The Christie NHS Foundation Trust's site on Wilmslow Road in Withington. The building is part of the Manchester Cancer Research Centre - a highly successful partnership between 3 powerhouses of innovation, The Christie, Cancer Research UK and The University of Manchester - and will be one of the top cancer research centres in the world.
World-leading scientists, clinicians and operational staff are now moving into a new £150m cancer research centre at The Christie NHS Foundation Trust's site on Wilmslow Road in Withington. The building is part of the Manchester Cancer Research Centre - a highly successful partnership between 3 powerhouses of innovation, The Christie, Cancer Research UK and The University of Manchester - and will be one of the top cancer research centres in the world.
Cannabinoid-based drug trial for brain tumours begins
Patients with aggressive brain tumours may be able to take part in a new trial of a cannabinoid-based drug, coordinated by the University of Birmingham.
Patients with aggressive brain tumours may be able to take part in a new trial of a cannabinoid-based drug, coordinated by the University of Birmingham.
Exploring ways to treat kidney cancer using patients’ own cells in new UCL-GSK collaboration
Researchers from the UCL Institute of Immunity & Transplantation (IIT) are leading a collaborative project with biopharma company GSK, aiming to discover innovative new kidney cancer treatments that use the patient's own cells.
Researchers from the UCL Institute of Immunity & Transplantation (IIT) are leading a collaborative project with biopharma company GSK, aiming to discover innovative new kidney cancer treatments that use the patient's own cells.
Incurable blood cancer trial finds new drug better than current second line treatments
Cancer Research UK Clinical Trials Unit-sponsored trial found new drug better for treating rare cancer for patients not responding to first line treatment Patients with an incurable blood cancer - pol
Cancer Research UK Clinical Trials Unit-sponsored trial found new drug better for treating rare cancer for patients not responding to first line treatment Patients with an incurable blood cancer - pol
First human trial of new Zika vaccine begins
The first participant has received a dose of a new Zika virus vaccine being trialled by the University of Liverpool at the Clinical Research Facility within the Royal Liverpool University Hospital, based on work at The University of Manchester. Although now not as prevalent as during its peak in 2016, Zika remains an ongoing threat, with thousands of cases of the mosquito-borne virus reported each year, mainly in countries close to the equator.
The first participant has received a dose of a new Zika virus vaccine being trialled by the University of Liverpool at the Clinical Research Facility within the Royal Liverpool University Hospital, based on work at The University of Manchester. Although now not as prevalent as during its peak in 2016, Zika remains an ongoing threat, with thousands of cases of the mosquito-borne virus reported each year, mainly in countries close to the equator.
International study recommends replacing skull section after treatment for a brain bleed
A major international trial has concluded that, where possible, surgeons should replace the removed section of the skull following surgery to treat a form of brain haemorrhage. This approach will save patients from having to undergo skull reconstruction further down the line.
A major international trial has concluded that, where possible, surgeons should replace the removed section of the skull following surgery to treat a form of brain haemorrhage. This approach will save patients from having to undergo skull reconstruction further down the line.
University spinout Complement Therapeutics secures ¤72 million to tackle diseases including leading cause of blindness
A preclinical biotechnology company, spun out of The University of Manchester, has announced the completion of a ¤72 million finance deal to develop the treatment of a leading cause of blindness.
A preclinical biotechnology company, spun out of The University of Manchester, has announced the completion of a ¤72 million finance deal to develop the treatment of a leading cause of blindness.
World first trial for patients with progressive MS launches in the UK
The first patients have been recruited for a revolutionary trial, led by UCL researchers, that will transform the way that treatments are tested for progressive multiple sclerosis (MS).
The first patients have been recruited for a revolutionary trial, led by UCL researchers, that will transform the way that treatments are tested for progressive multiple sclerosis (MS).
University of Warwick spin out company to develop world’s only testosterone patch for menopause
A company born out of ground-breaking research at The University of Warwick has raised almost £3 million of to develop a testosterone patch for people suffering from low libido and reduced zest for life due to the menopause.
A company born out of ground-breaking research at The University of Warwick has raised almost £3 million of to develop a testosterone patch for people suffering from low libido and reduced zest for life due to the menopause.
Game-changing research into new pancreatic cancer treatment underway
Pioneering research into a new game-changing treatment for those affected by pancreatic cancer has begun, giving hope to patients.
Pioneering research into a new game-changing treatment for those affected by pancreatic cancer has begun, giving hope to patients.
Finding new ways to diagnose childhood brain tumours
Cambridge researchers are using new techniques to distinguish different types of medulloblastoma, a type of brain tumour in children. With one in four children with this tumour type suffering long-term memory loss and speech issues after surgery, it is important that we work towards improving diagnostic methods which avoid surgery Jessica Taylor Funded by The Brain Tumour Charity, this research aims to develop new ways to diagnose medulloblastoma using minimally invasive methods, protecting the quality of life of children with this diagnosis.
Cambridge researchers are using new techniques to distinguish different types of medulloblastoma, a type of brain tumour in children. With one in four children with this tumour type suffering long-term memory loss and speech issues after surgery, it is important that we work towards improving diagnostic methods which avoid surgery Jessica Taylor Funded by The Brain Tumour Charity, this research aims to develop new ways to diagnose medulloblastoma using minimally invasive methods, protecting the quality of life of children with this diagnosis.
Opinion: Antidepressant withdrawal should be taken seriously - we’re investigating ways to help
Dr Mark Horowitz and Professor Joanna Moncrieff (both UCL Psychiatry) and Katharine Wallis from Queensland University examine in the Conversation the withdrawal symptoms of antidepressants and assess the advice supported by NHS England to safely stop taking them.
Dr Mark Horowitz and Professor Joanna Moncrieff (both UCL Psychiatry) and Katharine Wallis from Queensland University examine in the Conversation the withdrawal symptoms of antidepressants and assess the advice supported by NHS England to safely stop taking them.
Social Care Minister visits Imperial for launch of cancer breath test study
Minister for Social Care Helen Whately MP visited the Hammersmith Campus last week to discuss Imperial's research on diagnosing cancer.
Minister for Social Care Helen Whately MP visited the Hammersmith Campus last week to discuss Imperial's research on diagnosing cancer.
Antipsychotics are increasingly being prescribed to children - here’s why we should be concerned
Matthias Pierce , University of Manchester Kathryn Abel , University of Manchester An increasing number of young people in the UK are being referred to child and adolescent mental health services (CAMHS). Alongside this is the rising number of children prescribed medicines that treat mental illness. The evidence for the effectiveness and safety of these drugs comes almost entirely from studies in adults.
Matthias Pierce , University of Manchester Kathryn Abel , University of Manchester An increasing number of young people in the UK are being referred to child and adolescent mental health services (CAMHS). Alongside this is the rising number of children prescribed medicines that treat mental illness. The evidence for the effectiveness and safety of these drugs comes almost entirely from studies in adults.
Causeway Therapeutics Secures £8.75M for Phase 2 Trial of Tendinopathy Therapy
Causeway Therapeutics, a University of Glasgow spin-out specializing in tendon disease has raised £8.75M from investors to to advance development of microRNA therapeutics.
Causeway Therapeutics, a University of Glasgow spin-out specializing in tendon disease has raised £8.75M from investors to to advance development of microRNA therapeutics.
Clinical trial launches for new schizophrenia drug
A potential new treatment for schizophrenia developed by Cardiff University's Medicines Discovery Institute has successfully completed the first phase (single ascending dose) of a Phase 1 clinical trial.
A potential new treatment for schizophrenia developed by Cardiff University's Medicines Discovery Institute has successfully completed the first phase (single ascending dose) of a Phase 1 clinical trial.
India hospital network launched to initiate life-saving colon cancer trial
Twelve hospitals across country will be part of the network which will support the trial in India Cancer surgery experts today launched a network of hospitals across India to support a country-wide clinical trial exploring how giving colon cancer patients chemotherapy before surgery cuts their risk of the disease coming back.
Twelve hospitals across country will be part of the network which will support the trial in India Cancer surgery experts today launched a network of hospitals across India to support a country-wide clinical trial exploring how giving colon cancer patients chemotherapy before surgery cuts their risk of the disease coming back.
Roadmap sets out new global strategy for development of more effective coronavirus vaccines
Plan will accelerate a new approach to coronavirus vaccines research and development, to protect against COVID-19 variants and future pandemic threats from new coronaviruses It's vital that we continu
Plan will accelerate a new approach to coronavirus vaccines research and development, to protect against COVID-19 variants and future pandemic threats from new coronaviruses It's vital that we continu
Astex and Cardiff University announce drug discovery collaboration
The Medicines Discovery Institute at Cardiff University ("MDI") has announced a collaboration with Astex Pharmaceuticals (UK) ("Astex"), a pharmaceutical company dedicated to the discovery and development of novel small molecule therapeutics for oncology and diseases of the central nervous system. The multi-year, multimillion pound drug discovery research collaboration brings together the world-leading research expertise of Dr Emyr Lloyd-Evans & Dr Helen Waller-Evans in lysosomal biology, the drug discovery capabilities of the MDI and the structure-based drug discovery platform at Astex.
The Medicines Discovery Institute at Cardiff University ("MDI") has announced a collaboration with Astex Pharmaceuticals (UK) ("Astex"), a pharmaceutical company dedicated to the discovery and development of novel small molecule therapeutics for oncology and diseases of the central nervous system. The multi-year, multimillion pound drug discovery research collaboration brings together the world-leading research expertise of Dr Emyr Lloyd-Evans & Dr Helen Waller-Evans in lysosomal biology, the drug discovery capabilities of the MDI and the structure-based drug discovery platform at Astex.
Life changing research celebrated on World Cancer Day
The life-changing impact of cancer research done at the University is being celebrated on the first anniversary of the Leeds Cancer Research Centre.
The life-changing impact of cancer research done at the University is being celebrated on the first anniversary of the Leeds Cancer Research Centre.
University of Glasgow to lead international effort to advance cancer care and research
A team of experts from the University of Glasgow will lead a new international effort to improve cancer control and reduce global health inequalities.
A team of experts from the University of Glasgow will lead a new international effort to improve cancer control and reduce global health inequalities.
Three quarters of UK parents support routine chickenpox vaccine for children
Almost three quarters of UK parents would support a chickenpox vaccine being added to the childhood vaccination schedule, finds new research led by UCL and Keele University. The research team, led by Professor Helen Bedford (UCL Great Ormond Street Institute of Child Health) and Dr Sue Sherman (Keele University), surveyed nearly 600 parents on their attitudes towards a varicella (chickenpox) vaccine, including whether it should be routinely offered to all children, and whether they would be likely to accept it for their child.
Almost three quarters of UK parents would support a chickenpox vaccine being added to the childhood vaccination schedule, finds new research led by UCL and Keele University. The research team, led by Professor Helen Bedford (UCL Great Ormond Street Institute of Child Health) and Dr Sue Sherman (Keele University), surveyed nearly 600 parents on their attitudes towards a varicella (chickenpox) vaccine, including whether it should be routinely offered to all children, and whether they would be likely to accept it for their child.
Antiverse joins Cardiff Innovations
The biotech start-up Antiverse has joined Cardiff Innovations. Antiverse is striving to engineer the future of drug discovery, with an overarching goal to generate novel therapeutics that can change the course of people's lives.
The biotech start-up Antiverse has joined Cardiff Innovations. Antiverse is striving to engineer the future of drug discovery, with an overarching goal to generate novel therapeutics that can change the course of people's lives.
£2.2m for Glasgow Cancer Centre to help find new treatments
The development of new cancer treatments in Scotland is to receive major funding, providing future hope for people diagnosed with the disease.
The development of new cancer treatments in Scotland is to receive major funding, providing future hope for people diagnosed with the disease.
Major funding for Manchester will help find new cancer treatments
The search for new cancer treatments in Manchester is to receive a major funding investment of up to £3m, providing future hope for people diagnosed with the disease.
The search for new cancer treatments in Manchester is to receive a major funding investment of up to £3m, providing future hope for people diagnosed with the disease.
New precision therapy for bile duct cancer extends patients’ lives
A new personalised cancer treatment can radically improve the outlook for some patients with bile duct cancer, finds an international multicentre trial involving researchers at UCL and University College London Hospitals NHS Trust (UCLH).
A new personalised cancer treatment can radically improve the outlook for some patients with bile duct cancer, finds an international multicentre trial involving researchers at UCL and University College London Hospitals NHS Trust (UCLH).
Imperial-CNRS-Lille project to ’fast-track’ treatments for metabolic diseases
Imperial, France's National Centre for Scientific Research (CNRS) and the University of Lille are setting up a major project into metabolic diseases. Diseases linked with metabolism, such as diabetes, high blood pressure (hypertension) and obesity affect millions of people around the world. This new collaboration will aim to 'fast-track' treatments for these conditions.
Imperial, France's National Centre for Scientific Research (CNRS) and the University of Lille are setting up a major project into metabolic diseases. Diseases linked with metabolism, such as diabetes, high blood pressure (hypertension) and obesity affect millions of people around the world. This new collaboration will aim to 'fast-track' treatments for these conditions.
Testing wastewater for Covid-19 and communicable diseases
Wastewater monitoring for levels of Covid-19 in Wales have been expanded to include observation of the levels of communicable diseases and antimicrobial resistance in hospital wastewater.
Wastewater monitoring for levels of Covid-19 in Wales have been expanded to include observation of the levels of communicable diseases and antimicrobial resistance in hospital wastewater.
Experimental cancer therapy research continues at Birmingham
New and innovative ways to detect and treat cancer being trialled at Birmingham are to receive renewed funding from Cancer Research UK and the NIHR.
New and innovative ways to detect and treat cancer being trialled at Birmingham are to receive renewed funding from Cancer Research UK and the NIHR.
New simple method to diagnose adrenal insufficiency shaping way for improving the health of those affected
A new study led by the University of Sheffield in partnership with Sheffield Teaching Hospitals NHS Foundation Trust using saliva rather than blood to test for adrenal insufficiency offers significant improvements for screening patients The research shows how the new testing methods can make diagnosis more efficient at reduced cost The tests are being implemented in clinical practices in Sheffield and will be rolled out across the NHS A study in
A new study led by the University of Sheffield in partnership with Sheffield Teaching Hospitals NHS Foundation Trust using saliva rather than blood to test for adrenal insufficiency offers significant improvements for screening patients The research shows how the new testing methods can make diagnosis more efficient at reduced cost The tests are being implemented in clinical practices in Sheffield and will be rolled out across the NHS A study in
First UK proton beam therapy trial for breast cancer launches
Cambridge researchers are jointly leading the first UK trial to test the benefits of proton beam therapy for certain patients with breast cancer.
Cambridge researchers are jointly leading the first UK trial to test the benefits of proton beam therapy for certain patients with breast cancer.
Led team wins time on world’s most powerful computer
A UCL-led team of researchers is using the world's first exascale computer to identify a shortlist of potential new drugs for diseases and to better understand how stroke affects the brain. The supercomputer, Frontier, at the Oak Ridge Leadership Computing Facility in Tennessee, US, is the first in the world capable of an exaflop - a billion billion operations a second.
A UCL-led team of researchers is using the world's first exascale computer to identify a shortlist of potential new drugs for diseases and to better understand how stroke affects the brain. The supercomputer, Frontier, at the Oak Ridge Leadership Computing Facility in Tennessee, US, is the first in the world capable of an exaflop - a billion billion operations a second.
Trial of innovative CAR-T blood cancer treatment expanded
A clinical trial of a personalised therapy for blood cancer, led by researchers at UCL and University College London Hospitals, has been expanded enabling new groups of patients with a wider range of blood cancers to now receive the treatment. The new type of CAR T-cell therapy - where a patient's own immune system is 'reprogrammed' in order to fight their cancer - has already been shown to have promise for adult patients with a type of blood cancer called relapsed B-cell acute lymphoblastic leukaemia (B-ALL).
A clinical trial of a personalised therapy for blood cancer, led by researchers at UCL and University College London Hospitals, has been expanded enabling new groups of patients with a wider range of blood cancers to now receive the treatment. The new type of CAR T-cell therapy - where a patient's own immune system is 'reprogrammed' in order to fight their cancer - has already been shown to have promise for adult patients with a type of blood cancer called relapsed B-cell acute lymphoblastic leukaemia (B-ALL).
6 amazing scientific achievements at Imperial in 2022
From exploring magic mushrooms to answering COVID-19 questions, here are some of Imperial's biggest findings this year: Psilocybin "opens up" the brains of people with depression Psilocybin, the psychedelic component of magic mushrooms, was shown in April to increase brain connectivity in people with depression.
From exploring magic mushrooms to answering COVID-19 questions, here are some of Imperial's biggest findings this year: Psilocybin "opens up" the brains of people with depression Psilocybin, the psychedelic component of magic mushrooms, was shown in April to increase brain connectivity in people with depression.