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Pharmacology
Results 101 - 150 of 583.
RECOVERY Trial launches in South Africa
The world's largest clinical trial investigating treatments for COVID-19 has now launched in South Africa, with the first patient recruited today.
The world's largest clinical trial investigating treatments for COVID-19 has now launched in South Africa, with the first patient recruited today.
How SARS-Cov-2 is changed by antiviral treatments focus of new UCL study
Scientists at UCL will sequence the DNA of more than 10,000 samples of the SARS-CoV-2 virus to see if or how its genome is changed by different antiviral Covid-19 treatments.
Scientists at UCL will sequence the DNA of more than 10,000 samples of the SARS-CoV-2 virus to see if or how its genome is changed by different antiviral Covid-19 treatments.
Important message for students about new COVID-19 safety guidance
An update following the Prime Minister's announcement on 8 December of new Plan B safety measures. Please read this message carefully as it includes important information about what these changes mean for you.
An update following the Prime Minister's announcement on 8 December of new Plan B safety measures. Please read this message carefully as it includes important information about what these changes mean for you.
First UK trial to assess use of antivirals to treat COVID-19 set to be begin
The first clinical trial in the UK to investigate whether antiviral drugs could help reduce the severity of COVID-19 is due to start.
The first clinical trial in the UK to investigate whether antiviral drugs could help reduce the severity of COVID-19 is due to start.
Collaboration could enable cancer patients to get faster and more personalised treatment | University of Cambridge
GE Healthcare, the and Cambridge University Hospitals have agreed to collaborate on developing an application aiming to improve cancer care, with Cambridge providing clinical expertise and data to sup
GE Healthcare, the and Cambridge University Hospitals have agreed to collaborate on developing an application aiming to improve cancer care, with Cambridge providing clinical expertise and data to sup
Research shapes new miscarriage guidelines
Research led by the University of Birmingham has helped to shape guidelines which could mean thousands of women with prior miscarriage, and bleeding in early pregnancy, could be eligible for treatment with progesterone each year. The updated guidance, announced today by the National Institute for Health and Care Excellence (NICE), follows a review of evidence by NICE's independent guideline committee.
Research led by the University of Birmingham has helped to shape guidelines which could mean thousands of women with prior miscarriage, and bleeding in early pregnancy, could be eligible for treatment with progesterone each year. The updated guidance, announced today by the National Institute for Health and Care Excellence (NICE), follows a review of evidence by NICE's independent guideline committee.
The pain-free injection alternative gets a boost
Patches that deliver medicine through the skin could, in time, significantly reduce the need for injections, thanks to a three-year project launched this week.
Patches that deliver medicine through the skin could, in time, significantly reduce the need for injections, thanks to a three-year project launched this week.
Opinion: HPV jab cuts cervical cancer cases by almost 90% but one in 10 girls still haven’t had it
There needs to be a concerted effort to ensure all young people are protected against HPV, say Professor Helen Bedford (UCL Great Ormond Street Institute of Child Health) alongside Professor Carol Dezateux and Nicola Firman (both Queen Mary University of London).
There needs to be a concerted effort to ensure all young people are protected against HPV, say Professor Helen Bedford (UCL Great Ormond Street Institute of Child Health) alongside Professor Carol Dezateux and Nicola Firman (both Queen Mary University of London).
Gates Foundation funding for University to develop low cost manufacturing route to the promising COVID-19 therapy Molnupiravir
The University of Manchester has received $500,000 from the Bill & Melinda Gates Foundation to develop a low cost manufacturing route to Molnupiravir, a promising antiviral drug for the treatment of COVID-19, in order to widen access of the medicine to lower-income countries.
The University of Manchester has received $500,000 from the Bill & Melinda Gates Foundation to develop a low cost manufacturing route to Molnupiravir, a promising antiviral drug for the treatment of COVID-19, in order to widen access of the medicine to lower-income countries.
New spin-out company developing wound infection tests
A quick and simple test for bacterial infections is a step closer to market.
A quick and simple test for bacterial infections is a step closer to market.
Study exposes risks and benefits of virtual consultations with doctors
So-called 'telemedicine' is less diagnostically accurate than in-person consultations and could increase health inequalities and barriers to accessing appropriate care, finds a new study of rheumatology patients and clinicians.
So-called 'telemedicine' is less diagnostically accurate than in-person consultations and could increase health inequalities and barriers to accessing appropriate care, finds a new study of rheumatology patients and clinicians.
’Perfect for some but disastrous for others’: Patients and clinicians express concerns over phone and video consultations | University of Cambridge
A study of rheumatology patients and clinicians has found that while the majority found phone or video consultations more convenient than face-to-face consultations, they viewed so-called telemedicine
A study of rheumatology patients and clinicians has found that while the majority found phone or video consultations more convenient than face-to-face consultations, they viewed so-called telemedicine
Opinion: How Covid-19 threatens to undo years of progress in TB control
The Covid pandemic has proved that health systems are capable of making drastic changes when the need arises.
The Covid pandemic has proved that health systems are capable of making drastic changes when the need arises.
New immunotherapy insights for kidney cancer
Immune cell patterns have been discovered within tumours that can help predict if patients with kidney cancer will respond to immunotherapy, as part of a study co-led by researchers at UCL, the Francis Crick Institute and The Royal Marsden NHS Foundation Trust.
Immune cell patterns have been discovered within tumours that can help predict if patients with kidney cancer will respond to immunotherapy, as part of a study co-led by researchers at UCL, the Francis Crick Institute and The Royal Marsden NHS Foundation Trust.
Cardiff University to take leading role in COVID-19 antiviral trial
Cardiff University is to play a major role in UK-wide research into antiviral drugs that could help protect people from the worst symptoms of the virus.
Cardiff University is to play a major role in UK-wide research into antiviral drugs that could help protect people from the worst symptoms of the virus.
A third of leukaemia patients do not generate any antibody response to two doses of COVID-19 vaccination
A third of leukaemia patients do not generate any antibody response to two doses of COVID-19 vaccination, study shows A University of Birmingham-led study has shown that a third of patients with the most common type of leukaemia fail to generate any measurable antibody response following two doses of COVID-19 vaccination.
A third of leukaemia patients do not generate any antibody response to two doses of COVID-19 vaccination, study shows A University of Birmingham-led study has shown that a third of patients with the most common type of leukaemia fail to generate any measurable antibody response following two doses of COVID-19 vaccination.
Health professionals in Scotland will become leading experts in multimorbidity
A new generation of healthcare professionals will be trained to become world-leading experts in multimorbidity - one of the most significant healthcare challenges in both the UK and globally.
A new generation of healthcare professionals will be trained to become world-leading experts in multimorbidity - one of the most significant healthcare challenges in both the UK and globally.
Type 2 diabetes health checks down by 7.4 million due to UK’s covid restrictions in 2020
Manchester-based researchers estimate that between March and December 2020, 7.4 million fewer NICE recommended health care checks took place in UK general practices in people with type 2 diabetes, when compared to 10-year historical trends.
Manchester-based researchers estimate that between March and December 2020, 7.4 million fewer NICE recommended health care checks took place in UK general practices in people with type 2 diabetes, when compared to 10-year historical trends.
New guidelines to improve pregnancy trials will pave way for novel therapies for women and babies
A new grading system to monitor complications during clinical trials involving pregnant women, which will significantly improve their safety, has been co-developed by UCL researchers and an internati
A new grading system to monitor complications during clinical trials involving pregnant women, which will significantly improve their safety, has been co-developed by UCL researchers and an internati
Opinion: Why England should pursue a ’vaccine plus’ strategy
Instead of relying on vaccines alone, countries such as France and Germany are using extra measures to keep cases and deaths low - England should follow their example, argues Professor Christina Pagel (UCL Mathematics) in a co-authored piece with Professor Martin McKee.
Instead of relying on vaccines alone, countries such as France and Germany are using extra measures to keep cases and deaths low - England should follow their example, argues Professor Christina Pagel (UCL Mathematics) in a co-authored piece with Professor Martin McKee.
Heroin overdose deaths often happen shortly after leaving hospital
Drug-related deaths are four times more likely to occur in the two days after hospital discharge than at any other time among users of opioids such as heroin, according to research led by UCL, Public Health England (PHE)* and King's College London. The peer-reviewed study, published today in PLOS Medicine, looked at data from 13,609 adults in England, who were aged between 18 and 64 and died after using non-prescribed opioids between 2010 and 2019.
Drug-related deaths are four times more likely to occur in the two days after hospital discharge than at any other time among users of opioids such as heroin, according to research led by UCL, Public Health England (PHE)* and King's College London. The peer-reviewed study, published today in PLOS Medicine, looked at data from 13,609 adults in England, who were aged between 18 and 64 and died after using non-prescribed opioids between 2010 and 2019.
Oxford announces expansion of graduate access programme
For the second year in a row, The British Medical Journal have selected a publication co-authored by Oxford researchers for their prestigious UK Research Paper of the Year Award.
For the second year in a row, The British Medical Journal have selected a publication co-authored by Oxford researchers for their prestigious UK Research Paper of the Year Award.
New state-of-the-art centre for immune disease opens
UCL scientists investigating the immune system will work alongside doctors, nurses and patients from the Royal Free Hospital, in a unique partnership that will enable new treatments to be developed more quickly for global health problems, including Covid-19, diabetes and cancer.
UCL scientists investigating the immune system will work alongside doctors, nurses and patients from the Royal Free Hospital, in a unique partnership that will enable new treatments to be developed more quickly for global health problems, including Covid-19, diabetes and cancer.
Opinion: Long-term antidepressant use is effective, but many people can come off them safely
Many people on depressants continue taking them for fear of having a relapse but new research could help doctors and patients make more informed decisions, say Dr Gemma Lewis and Professor Glyn Lewis (both UCL Psychiatry). The number of prescriptions written for antidepressants in wealthy countries has doubled in the past 20 years.
Many people on depressants continue taking them for fear of having a relapse but new research could help doctors and patients make more informed decisions, say Dr Gemma Lewis and Professor Glyn Lewis (both UCL Psychiatry). The number of prescriptions written for antidepressants in wealthy countries has doubled in the past 20 years.
Moonshot initiative to develop affordable COVID-19 antivirals gets funding boost
The COVID Moonshot, a non-profit, open-science consortium of scientists from around the world dedicated to the discovery of globally affordable and easily-manufactured antiviral drugs against COVID-1
The COVID Moonshot, a non-profit, open-science consortium of scientists from around the world dedicated to the discovery of globally affordable and easily-manufactured antiviral drugs against COVID-1
Early trial of multivariant COVID-19 vaccine booster begins in Manchester
A phase one trial of a multivariant COVID-19 Vaccine has been launched by US pharmaceutical company Gritstone in collaboration with The University of Manchester and Manchester University NHS Foundation Trust.
A phase one trial of a multivariant COVID-19 Vaccine has been launched by US pharmaceutical company Gritstone in collaboration with The University of Manchester and Manchester University NHS Foundation Trust.
New combination of old drugs improves survival of prostate cancer
Giving the drug abiraterone alongside standard hormone therapy helps men with high-risk prostate cancer that has not spread elsewhere in the body to live longer, according to preliminary results of a UCL-led trial. This result from the STAMPEDE trial, based at the MRC Clinical Trials Unit at UCL and funded by Cancer Research UK and MRC, was presented today at the European Society for Medical Oncology (ESMO) Congress.
Giving the drug abiraterone alongside standard hormone therapy helps men with high-risk prostate cancer that has not spread elsewhere in the body to live longer, according to preliminary results of a UCL-led trial. This result from the STAMPEDE trial, based at the MRC Clinical Trials Unit at UCL and funded by Cancer Research UK and MRC, was presented today at the European Society for Medical Oncology (ESMO) Congress.
New study will use artificial intelligence to improve treatments for people with multiple long-term conditions
The NIHR has awarded £2.5 million for new research led by the University of Birmingham that will use artificial intelligence (AI) to produce computer programmes and tools that will help doctors improve the choice of drugs in patients with clusters of multiple long-term conditions.
The NIHR has awarded £2.5 million for new research led by the University of Birmingham that will use artificial intelligence (AI) to produce computer programmes and tools that will help doctors improve the choice of drugs in patients with clusters of multiple long-term conditions.
Dog vaccination essential for preventing rabies spread to humans and animals
A coordinated and sustained programme of dog vaccination against rabies, is effective in preventing transmission of the deadly virus to humans and among animals, and remains key to rabies elimination. New research, led by the University of Glasgow in collaboration with Ifakara Health Institute and Imperial College London, published today in Applied Ecology, found that rabies incidence in both humans and domestic dogs decreased during a period of sustained dog vaccination in southeast Tanzania, despite incidences of ongoing wildlife rabies infections.
A coordinated and sustained programme of dog vaccination against rabies, is effective in preventing transmission of the deadly virus to humans and among animals, and remains key to rabies elimination. New research, led by the University of Glasgow in collaboration with Ifakara Health Institute and Imperial College London, published today in Applied Ecology, found that rabies incidence in both humans and domestic dogs decreased during a period of sustained dog vaccination in southeast Tanzania, despite incidences of ongoing wildlife rabies infections.
Global COVID-19 surgery study scoops scientific world record
A study led by University of Birmingham experts has been awarded the Guinness World Records title for the world's largest scientific collaboration - involving over 140,000 patients in 116 countries.
A study led by University of Birmingham experts has been awarded the Guinness World Records title for the world's largest scientific collaboration - involving over 140,000 patients in 116 countries.
Woman who has lived with 30 year cough receives world-first dose of potential new treatment
A 70-year-old woman, forced to live with cough since her 40s, is 'excited' to be the first person in the world to receive a potential new cough treatment at the NIHR Manchester Clinical Research Facility (CRF) .
A 70-year-old woman, forced to live with cough since her 40s, is 'excited' to be the first person in the world to receive a potential new cough treatment at the NIHR Manchester Clinical Research Facility (CRF) .
New study to test third COVID-19 vaccine for people with weakened immune systems
A new clinical trial led by the Universities of Birmingham and Glasgow has launched in the UK to determine whether a third dose of vaccine will improve the immune response for people who have weakened immune systems. The study, OCTAVE DUO, will offer people who are immunosuppressed or immunocompromised a Pfizer, Moderna or Novavax vaccine to determine whether this will give a stronger immune response than two doses.
A new clinical trial led by the Universities of Birmingham and Glasgow has launched in the UK to determine whether a third dose of vaccine will improve the immune response for people who have weakened immune systems. The study, OCTAVE DUO, will offer people who are immunosuppressed or immunocompromised a Pfizer, Moderna or Novavax vaccine to determine whether this will give a stronger immune response than two doses.
Event - Today
Erin James, University of Sussex's 'Stuart Hall Fellow', to perform at Brighton Festival
Erin James, University of Sussex's 'Stuart Hall Fellow', to perform at Brighton Festival
Innovation - Today
National Grid and University of Manchester pilot drone-mounted electric field sensors for pylon inspections
National Grid and University of Manchester pilot drone-mounted electric field sensors for pylon inspections