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Health - Pharmacology - 02.02.2023
Health - Pharmacology - 30.01.2023
Pharmacology - Health - 30.01.2023 
Major trials to test effectiveness of cannabidiol on psychosis
A global study involving three clinical trials will investigate the effectiveness of cannabidiol (CBD) in treating people with psychosis or psychotic symptoms, thanks to a multi-million pound grant to Oxford University. Wellcome has awarded Oxford's Department of Psychiatry £16.5 million for the STEP (Stratification & Treatment in Early Psychosis) programme, as part of its support for mental health research.
Pharmacology - Health - 27.01.2023 
New blood test could save lives of heart attack victims
Researchers from the Herring group in Oxford's Department of Physiology, Anatomy and Genetics have developed a blood test that measures stress hormone levels after heart attacks. The test - costing just £10 - could ensure patients receive timely life-saving treatment. Cardiovascular disease is the main cause of death in the UK.
Health - Pharmacology - 27.01.2023 
Loyalty card data could help identify ovarian cancer symptoms sooner
Loyalty card data on over-the-counter medicine purchases could help spot ovarian cancer cases earlier, finds a new study involving UCL researchers. The first-of-its kind study, published in JMIR Public Health and Surveillance , found that pain and indigestion medication purchases were higher in women who were subsequently diagnosed with ovarian cancer, compared to women who did not have ovarian cancer.
Health - Pharmacology - 26.01.2023
Health - Pharmacology - 23.01.2023 
COVID-19 patients may retain elevated risk of death 18 months after infection
COVID-19 is associated with higher risks of cardiovascular disease and death in the shortand long-term, according to a study in nearly 160,000 unvaccinated participants co-led by a UCL researcher. The study, published today in Cardiovascular Research , a journal of the European Society of Cardiology, investigated outcomes in a group of adults mostly aged in their 60s.
Pharmacology - Psychology - 23.01.2023 
Scientists explain emotional ’blunting’ caused by common antidepressants
Scientists have worked out why common anti-depressants cause around a half of users to feel emotionally -blunted-. In a study published today, they show that the drugs affect reinforcement learning, an important behavioural process that allows us to learn from our environment. According to the NHS, more than 8.3 million patients in England received an antidepressant drug in 2021/22.
Health - Pharmacology - 20.01.2023
Health - Pharmacology - 20.01.2023
Pharmacology - Health - 19.01.2023 
Chemotherapy before surgery cuts risk of colon cancer returning, trial finds
Patients with early stage colon cancer benefit from 6 weeks of chemotherapy before surgery Giving colon cancer patients chemotherapy before surgery cuts their risk of the disease coming back, according to the results of a Cancer Research UK-funded clinical trial. The FOxTROT trial showed that giving colon cancer patients chemotherapy before rather than after surgery reduced the chance of cancer returning within 2 years by 28%.
Health - Pharmacology - 17.01.2023 
Vaccination shown to protect against pregnancy complications from COVID-19 Omicron variant
The global network led by the Oxford Maternal and Perinatal Health Institute (OMPHI) at the University of Oxford has today published, in The Lancet , the results of the ' 2022 INTERCOVID Study ' conducted in 41 hospitals across 18 countries. To evaluate the impact of the COVID-19 Omicron variant on maternal and neonatal outcomes the researchers studied 1,545 pregnant women diagnosed with the variant and 3,073 non-diagnosed, concomitant pregnant women as controls.
Pharmacology - Psychology - 17.01.2023
Pharmacology - Health - 11.01.2023 
Criteria to diagnose common cause of sudden vision loss
A universal criteria for diagnosing the blinding eye condition, optic neuritis, has been developed by a UCL-led team of researchers. Optic neuritis is inflammation in the optic nerve and is a common cause of sudden and acute vision loss, affecting around 6 in 100,000 people. It may occur at any age with vision loss typically occurring over several hours or a few days , from onset Sometimes optic neuritis is caused by multiple sclerosis (MS), but it can also be triggered by many other conditions.
Health - Pharmacology - 11.01.2023 
Artificial pancreas successfully trialled for use by type 2 diabetes patients
Cambridge scientists have successfully trialled an artificial pancreas for use by patients living with type 2 diabetes. The device - powered by an algorithm developed at the University of Cambridge - doubled the amount of time patients were in the target range for glucose compared to standard treatment and halved the time spent experiencing high glucose levels.
Pharmacology - Health - 10.01.2023
Health - Pharmacology - 10.01.2023 
Cough medicine could be used in new treatment for Parkinson’s disease
A large-scale Phase 3 clinical trial to establish ambroxol's potential to slow the progression of Parkinson's disease, will start in early 2023. Ambroxol is a drug which is currently used to treat respiratory conditions. It promotes the clearance of mucus, eases coughing and has anti-inflammatory properties.
Health - Pharmacology - 05.01.2023
Pharmacology - Health - 23.12.2022
Health - Pharmacology - 19.12.2022
Pharmacology
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Combined steroid and statin treatment could reduce ’accelerated ageing’ in preterm babies, study in rats suggests
Potentially life-saving steroids commonly given to preterm babies also increase the risk of long-term cardiovascular problems, but a new study in rats has found that if given in conjunction with statins, their positive effects remain while the potential negative side-effects are -weeded out-. "We are not saying to stop using glucocorticoids, as they are clearly a life-saving treatment.
Potentially life-saving steroids commonly given to preterm babies also increase the risk of long-term cardiovascular problems, but a new study in rats has found that if given in conjunction with statins, their positive effects remain while the potential negative side-effects are -weeded out-. "We are not saying to stop using glucocorticoids, as they are clearly a life-saving treatment.
New study into Tuberculosis membrane molecules will aid drug delivery
A new method to aid in the development of antibiotics for tuberculosis (TB) infections has been devised. TB rivals covid-19 as the biggest infectious disease killer of humans, claiming millions of lives each year. Now, ground-breaking research from the Universities of Warwick and Toulouse has identified a new method to help tackle this global issue.
A new method to aid in the development of antibiotics for tuberculosis (TB) infections has been devised. TB rivals covid-19 as the biggest infectious disease killer of humans, claiming millions of lives each year. Now, ground-breaking research from the Universities of Warwick and Toulouse has identified a new method to help tackle this global issue.
A global study involving three clinical trials will investigate the effectiveness of cannabidiol (CBD) in treating people with psychosis or psychotic symptoms, thanks to a multi-million pound grant to Oxford University. Wellcome has awarded Oxford's Department of Psychiatry £16.5 million for the STEP (Stratification & Treatment in Early Psychosis) programme, as part of its support for mental health research.
Researchers from the Herring group in Oxford's Department of Physiology, Anatomy and Genetics have developed a blood test that measures stress hormone levels after heart attacks. The test - costing just £10 - could ensure patients receive timely life-saving treatment. Cardiovascular disease is the main cause of death in the UK.
Loyalty card data on over-the-counter medicine purchases could help spot ovarian cancer cases earlier, finds a new study involving UCL researchers. The first-of-its kind study, published in JMIR Public Health and Surveillance , found that pain and indigestion medication purchases were higher in women who were subsequently diagnosed with ovarian cancer, compared to women who did not have ovarian cancer.
Loyalty card data could help to identify ovarian cancer symptoms sooner
Loyalty card data on over-the-counter medicine purchases could help spot ovarian cancer cases earlier, an Imperial College London-led study suggests. The study of almost 300 women found that pain and indigestion medication purchases were higher in women who were subsequently diagnosed with ovarian cancer, compared to women who did not have ovarian cancer.
Loyalty card data on over-the-counter medicine purchases could help spot ovarian cancer cases earlier, an Imperial College London-led study suggests. The study of almost 300 women found that pain and indigestion medication purchases were higher in women who were subsequently diagnosed with ovarian cancer, compared to women who did not have ovarian cancer.
COVID-19 is associated with higher risks of cardiovascular disease and death in the shortand long-term, according to a study in nearly 160,000 unvaccinated participants co-led by a UCL researcher. The study, published today in Cardiovascular Research , a journal of the European Society of Cardiology, investigated outcomes in a group of adults mostly aged in their 60s.
Scientists have worked out why common anti-depressants cause around a half of users to feel emotionally -blunted-. In a study published today, they show that the drugs affect reinforcement learning, an important behavioural process that allows us to learn from our environment. According to the NHS, more than 8.3 million patients in England received an antidepressant drug in 2021/22.
’Remarkable’ results in colon cancer trial
Giving colon cancer patients chemotherapy before surgery cuts the risk of the disease coming back, according to the results of a new clinical trial. The FOxTROT trial, a collaborative study by scientists at Leeds and the University of Birmingham, showed that giving colon cancer patients chemotherapy before rather than after surgery reduced the chance of cancer returning within 2 years by 28%.
Giving colon cancer patients chemotherapy before surgery cuts the risk of the disease coming back, according to the results of a new clinical trial. The FOxTROT trial, a collaborative study by scientists at Leeds and the University of Birmingham, showed that giving colon cancer patients chemotherapy before rather than after surgery reduced the chance of cancer returning within 2 years by 28%.
Does COVID really damage your immune system and make you more vulnerable to infections? The evidence is lacking
Over the past month or two, many northern hemisphere countries including the US and the UK have seen a large wave of respiratory viral infections. These include RSV ( respiratory syncytial virus ), flu and COVID in all ages, as well as bacterial infections such as strep A in children. Sometimes these infections can be very serious.
Over the past month or two, many northern hemisphere countries including the US and the UK have seen a large wave of respiratory viral infections. These include RSV ( respiratory syncytial virus ), flu and COVID in all ages, as well as bacterial infections such as strep A in children. Sometimes these infections can be very serious.
Patients with early stage colon cancer benefit from 6 weeks of chemotherapy before surgery Giving colon cancer patients chemotherapy before surgery cuts their risk of the disease coming back, according to the results of a Cancer Research UK-funded clinical trial. The FOxTROT trial showed that giving colon cancer patients chemotherapy before rather than after surgery reduced the chance of cancer returning within 2 years by 28%.
The global network led by the Oxford Maternal and Perinatal Health Institute (OMPHI) at the University of Oxford has today published, in The Lancet , the results of the ' 2022 INTERCOVID Study ' conducted in 41 hospitals across 18 countries. To evaluate the impact of the COVID-19 Omicron variant on maternal and neonatal outcomes the researchers studied 1,545 pregnant women diagnosed with the variant and 3,073 non-diagnosed, concomitant pregnant women as controls.
New study tests impact of coming off antidepressants on mood and thinking patterns
University psychologists aiming to improve help for people withdrawing from antidepressants want volunteers to come forward to participate in the new study. New research being led by a team of psychologists at the University of Bath hopes to provide evidence to improve the clinical care of people in the process of withdrawing from antidepressants.
University psychologists aiming to improve help for people withdrawing from antidepressants want volunteers to come forward to participate in the new study. New research being led by a team of psychologists at the University of Bath hopes to provide evidence to improve the clinical care of people in the process of withdrawing from antidepressants.
A universal criteria for diagnosing the blinding eye condition, optic neuritis, has been developed by a UCL-led team of researchers. Optic neuritis is inflammation in the optic nerve and is a common cause of sudden and acute vision loss, affecting around 6 in 100,000 people. It may occur at any age with vision loss typically occurring over several hours or a few days , from onset Sometimes optic neuritis is caused by multiple sclerosis (MS), but it can also be triggered by many other conditions.
Cambridge scientists have successfully trialled an artificial pancreas for use by patients living with type 2 diabetes. The device - powered by an algorithm developed at the University of Cambridge - doubled the amount of time patients were in the target range for glucose compared to standard treatment and halved the time spent experiencing high glucose levels.
Worrying rise in antipsychotic prescriptions for children and young people
The proportion of children and adolescents prescribed antipsychotics in English general practice doubled from 0.06% to 0.11% between 2000 and 2019, find researchers at The University of Manchester's Centre for Women's Mental Health. The drugs, which have a tranquillising effect, are frequently used in adults to treat major mental illness, such as schizophrenia.
The proportion of children and adolescents prescribed antipsychotics in English general practice doubled from 0.06% to 0.11% between 2000 and 2019, find researchers at The University of Manchester's Centre for Women's Mental Health. The drugs, which have a tranquillising effect, are frequently used in adults to treat major mental illness, such as schizophrenia.
A large-scale Phase 3 clinical trial to establish ambroxol's potential to slow the progression of Parkinson's disease, will start in early 2023. Ambroxol is a drug which is currently used to treat respiratory conditions. It promotes the clearance of mucus, eases coughing and has anti-inflammatory properties.
Targeting variant of common protein may dramatically boost effectiveness of breast cancer treatment
A rare variant of a protein present in nearly all human cells may hold the key to improving the effectiveness of breast cancer treatment, according to University of Manchester research funded by Breast Cancer Now. This discovery, published today (5 January 2023) in Oncogene, is the first time scientists have identified that targeting RAC1B, a variant of the RAC1 protein, could be a potential way of improving treatment for breast cancer.
A rare variant of a protein present in nearly all human cells may hold the key to improving the effectiveness of breast cancer treatment, according to University of Manchester research funded by Breast Cancer Now. This discovery, published today (5 January 2023) in Oncogene, is the first time scientists have identified that targeting RAC1B, a variant of the RAC1 protein, could be a potential way of improving treatment for breast cancer.
COVID-19 treatments have long-term benefits for patients
Drugs used to treat critically ill COVID-19 patients in hospital have long-term benefits, according to new research. The study, published in JAMA , found that treating critically ill patients with the drugs tocilizumab and sarilumab reduced the risk of dying over six months by a quarter, compared to those who did not receive these treatments.
Drugs used to treat critically ill COVID-19 patients in hospital have long-term benefits, according to new research. The study, published in JAMA , found that treating critically ill patients with the drugs tocilizumab and sarilumab reduced the risk of dying over six months by a quarter, compared to those who did not receive these treatments.
First-line defences against COVID-19 are short-lived and may explain reinfection
A new study finds that antibodies produced in the nose decline 9 months after infection, while those found in the blood last at least a year. A new study finds that antibodies produced in the nose decline nine months after COVID-19 infection, while antibodies found in the blood last at least a year.
A new study finds that antibodies produced in the nose decline 9 months after infection, while those found in the blood last at least a year. A new study finds that antibodies produced in the nose decline nine months after COVID-19 infection, while antibodies found in the blood last at least a year.
