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Health - Pharmacology - 12.06.2024 - Today
New research centre aims to improve heart disease treatment
A new research collaboration is setting out to develop computational tools to improve treatments for one of the world's most common causes of death. The University of Glasgow will lead the newly-established EPSRC Centre for Future PCI Planning, which aims to improve outcomes from a frequently-performed treatment for heart artery disease.

Pharmacology - Health - 07.06.2024
Study claiming antidepressant withdrawal is uncommon fails to account for long term users
Study claiming antidepressant withdrawal is uncommon fails to account for long term users
Comment: Study claiming antidepressant withdrawal is uncommon fails to account for long term users Writing in The Conversation, Professor Joanna Moncrieff and Dr Mark Horowitz (both UCL Psychiatry) respond to new research that antidepressant withdrawal is less common than previously thought by highlighting the risks among long-term users.

Health - Pharmacology - 07.06.2024
Major cause of inflammatory bowel disease discovered
UK researchers have discovered a new biological pathway which drives inflammatory bowel disease (IBD) and could be targeted with existing drugs. The work, carried out by researchers at the Francis Crick Institute, working with UCL and Imperial College London, uncovered a region of DNA which effectively dials up the activity of specific white blood cells, driving inflammation and increasing IBD risk.

Health - Pharmacology - 06.06.2024
Major cause of inflammatory bowel disease discovered
Major cause of inflammatory bowel disease discovered
A new biological pathway that is a principal driver of inflammatory bowel disease (IBD) and related conditions, and which can be targeted using existing drugs, has been discovered by researchers at UCL, the Francis Crick Institute and Imperial College London. About 5% of the world's population, and one in ten people in the UK, are currently affected by an autoimmune disease, such as IBD, the umbrella term for Crohn's disease and ulcerative colitis, which cause swelling and irritation of the digestive tract.

Health - Pharmacology - 30.05.2024
New immunotherapy could treat cancer in the bone
A new type of immunotherapy, developed by UCL researchers, has shown promising preclinical results against a bone cancer called osteosarcoma, as part of a study in mice. Osteosarcoma is the most common bone cancer in teenagers but is still relatively rare, with around 160 new cases each year in the UK.

Pharmacology - 20.05.2024
How beeswax could help families in warzones
Beeswax and local herbs could be crucial in helping families living in conflict zones store food, according to scientists from Cardiff University and Kharkiv Polytechnic Institute of National Technical University, Ukraine.

Pharmacology - 16.05.2024
Scientists brew killer bee beer
A new beer is being brewed by microbiologists, using extracts found in killer bees from Namibia. Scientists from Cardiff University have used brewer's yeast that resides in the gut microbiome of killer honeybees in Namibia and applied it to develop a unique craft beer. The Cardiff microbiologists originally visited Namibia as part of a project that unites Cardiff University and the University of Namibia for sustainable environmental development, when the scientists became interested in the Africanised honey bee - also known as the killer bee.

Health - Pharmacology - 14.05.2024
’Weight loss’ drug semaglutide linked to better heart health
The weight loss drug semaglutide delivers cardiovascular benefits irrespective of starting weight and amount of weight lost, according to preliminary findings from a UCL-led research team. The findings, presented at this year's European Congress on Obesity (ECO), suggest that even people with mild obesity or those not losing weight are likely to gain some cardiovascular advantage.

Health - Pharmacology - 13.05.2024
Birth by C-section more than doubles odds of measles vaccine failure
Researchers say it is vital that children born by caesarean section receive two doses of the measles vaccine for robust protection against the disease. A study by the University of Cambridge, UK, and Fudan University, China, has found that a single dose of the measles jab is up to 2.6 times more likely to be completely ineffective in children born by C-section, compared to those born naturally.

Health - Pharmacology - 12.05.2024
Heart failure device could remotely monitor patients and prevent hospitalisation
A brand-new monitoring device for patients with heart failure may be able to detect signs of fluid overload, and could be used to monitor patients and help prevent hospital admissions, according to a new study.

Health - Pharmacology - 08.05.2024
A third Covid vaccine dose improves defence for some clinically extremely vulnerable patients
A major clinical trial has found that an additional COVID 19 vaccine dose led to the majority of clinically extremely vulnerable people mounting defensive antibodies against Covid-19. New research published in The Lancet Rheumatology from the OCTAVE DUO research trial co-led by the University of Birmingham and University of Glasgow found that vaccine boosters led to improved antibody responses among many groups of immunocompromised and immunosuppressed patients.

Health - Pharmacology - 06.05.2024
New vaccine effective against coronaviruses that haven’t even emerged yet
Researchers have developed a new vaccine technology that has been shown in mice to provide protection against a broad range of coronaviruses with potential for future disease outbreaks - including ones we don't even know about Our focus is to create a vaccine that will protect us against the next coronavirus pandemic, and have it ready before the pandemic has even started.

Health - Pharmacology - 01.05.2024
Immune cells hunt down cancer around the body
Scientists have discovered the key features of immune B cells which make them successful at targeting tumours - including when cancer has spread to a different part of the body. Published in Nature Immunology , the researchers have developed a computational tool to identify these anti-cancer immune cells which could lead to improved, personalised immunotherapies.

Health - Pharmacology - 01.05.2024
Liver study pinpoints cell that helps healing process
A type of cell responsible for repairing damaged liver tissue has been uncovered for the first time by a team of scientists, including Professor Rajiv Jalan (UCL Liver & Digestive Health). The study, published in Nature , showed how these new-found cells migrate to the site of damage, providing new insights into the way the liver heals itself.

Health - Pharmacology - 29.04.2024
Exercise programmes benefit a wide range of long-term health conditions
A new study looking at health data from the last 20 years has highlighted the benefits of exercise programmes for individuals living with long-term health conditions. Drawing on a comprehensive overview of published evidence spanning 39 different long-term conditions - and encompassing 990 randomised controlled trials and over 900,000 patients - the research underscores the fundamental role of exercise in enhancing the wellbeing of individuals living with long-term health conditions.

Health - Pharmacology - 26.04.2024
New treatment for brain tumours approved following decades of work
The first ever targeted treatment for brain tumours in children has been approved for NHS patients, following over 20 years of research by a UCL clinician scientist. Professor Darren Hargrave, who is a researcher at the UCL Great Ormond Street Institute of Child Health and consultant at Great Ormond Street Hospital for Children (GOSH), was the Chair of the TADPOLE-G trial steering group, alongside researchers across the world.

Health - Pharmacology - 26.04.2024
Azithromycin and preventing chronic lung disease in premature babies
The early use of azithromycin does not prevent the development of chronic lung disease in premature babies, finds new research by Cardiff University. The largest clinic trial for azithromycin and chronic lung diseases in premature babies has provided definitive answers to whether azithromycin can decrease rates of chronic lung disease in prematurely born babies.

Health - Pharmacology - 19.04.2024
Training AI models to answer ’what if’’ questions could improve medical treatments
Machines can learn not only to make predictions, but to handle causal relationships. An international research team shows how this could make medical treatments safer, more efficient, and more personalised. Artificial intelligence techniques can be helpful for multiple medical applications, such as radiology or oncology, where the ability to recognise patterns in large volumes of data is vital.

Pharmacology - Health - 17.04.2024
Antipsychotics for dementia linked to more harms than previously acknowledged
Risks highest soon after starting drugs, underscoring need for increased caution in early stages of treatment, say experts Antipsychotic use in people with dementia is associated with higher risks of a wide range of serious health outcomes compared with non-use, according to a new study from a collaboration across the Universities of Manchester, Nottingham, Edinburgh and Dundee.

Health - Pharmacology - 08.04.2024
Long COVID leaves telltale traces in the blood
People with long COVID have distinct patterns of inflammation detectable in the blood, which could potentially be targeted with immune therapies. Findings from the largest UK study of patients hospitalised with SARS-CoV-2 infection show that long COVID leads to ongoing inflammation which can be detected in the blood.
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