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Health - Social Sciences - 08.12.2023
Engaging heterosexual men more effectively could slash HIV infections in Uganda
Engaging heterosexual men more effectively could slash HIV infections in Uganda
A study looking at 15 years of HIV transmission and suppression in Uganda reveals how closing gender gaps in treatment could slash infection rates. Providing more heterosexual men with easy access to HIV treatment and care could help to suppress the virus and rapidly cut transmission to their female partners, shows a new study published in Nature Microbiology .

Life Sciences - Health - 08.12.2023
Ancient DNA reveals how a chicken virus evolved to become more deadly
An international team of scientists led by geneticists and disease biologists from the University of Oxford and LMU Munich have used ancient DNA to trace the evolution of Marek's Disease Virus (MDV). This global pathogen causes fatal infections in unvaccinated chickens and costs the poultry industry over $1 billion per year.

Health - Pharmacology - 06.12.2023
Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses
Researchers have discovered that misreading of therapeutic mRNAs by the cell's decoding machinery can cause an unintended immune response in the body. They have identified the sequence within the mRNA that causes this to occur and found a way to prevent 'off-target' immune responses to enable the safer design of future mRNA therapeutics.

Health - Pharmacology - 05.12.2023
Individually targeted therapies may improve treatment for psychosis
A paper from the University of Southampton examining how best to treat psychosis has concluded that a greater range of individually targeted therapies could improve outcomes for patients. The research questions if Cognitive Behaviour Therapy (CBTp) for psychosis should remain the dominant treatment and suggests that, in the future, big data and artificial intelligence may help to develop a range of more bespoke therapies.

Health - Life Sciences - 05.12.2023
Blood test to identify individuals at risk of developing Parkinson's disease
Blood test to identify individuals at risk of developing Parkinson’s disease
Researchers develop a blood test to identify individuals at risk of developing Parkinson's disease Research carried out at Oxford'sá Nuffield Department of Clinical Neurosciences áhas led to the development of a new blood-based test to identify the pathology that triggers Parkinson's disease before the main symptoms occur.

Health - Life Sciences - 05.12.2023
Fatty foods can impair the body’s response to everyday stress - study
Eating fatty foods during stressful periods can impair the body's 'recovery' from the effects of stress, new research suggests. Different findings from a study, published recently in Frontiers in Nutrition and Nutrients , have shown that consuming foods high in fat before a mentally stressful episode can reduce brain oxygenation and cause poorer vascular function in adults.

Health - 04.12.2023
Meditation training can support wellbeing in older adults
Following an 18-month meditation programme can improve the wellbeing of older adults, finds a new randomised controlled trial by an international team co-led by UCL. The findings, published in PLOS ONE , show that meditation can improve people's awareness, connection to others, and insight. While the meditation training did not confer significant benefits on two commonly used measures of psychological wellbeing and quality of life, the researchers say their findings may reveal limitations in existing methods of tracking wellbeing.

Health - 30.11.2023
Patients with improved discharge planning less likely to be readmitted, finds study
Patients given transitional care before and during discharge from hospital - such as joint discharge planning follow up visits or phone calls - are less likely to be readmitted according to University of Manchester researchers. meta study of data from 126trials with 97, 408participants, published in JAMA Network Open today (30/11/23) showed the interventions were associated with significant reductions in the odds of readmissions at 180 days after discharge.

Health - Agronomy / Food Science - 30.11.2023
Largest study of its kind shows leafy greens may decrease bowel cancer risk
Increasing the amount of folate through our diet or taking supplements could help to reduce bowel cancer risk. These are the findings of new research , co-led by Dr Konstantinos Tsilidis from the School of Public Health at Imperial College London. It suggests that increasing the intake of folate - which can be found in leafy greens, such as spinach, cabbage and broccoli - could help to reduce the risk of colorectal cancer by up to 7%.

Health - Life Sciences - 30.11.2023
Brain waves usually found in sleep can protect against epileptic activity
Slow waves that usually only occur in the brain during sleep are also present during wakefulness in people with epilepsy and may protect against increased brain excitability associated with the condition, finds a new study led by researchers at UCL.

Health - Pharmacology - 30.11.2023
Study identifies barriers that limit young men at HIV risk from taking preventative drug
A new qualitative study from Bath psychologists suggests a lack of information and perceived necessity, as well as awkwardness, are impacting uptake of PrEP. Published on Thursday 30 November 2023 Last updated on Thursday 30 November 2023 Results of a qualitative research study into the uptake of PrEP - a drug which stops HIV infecting the body - suggests that more needs to be done to breakdown barriers to access for the potentially lifesaving medication.

Health - Life Sciences - 29.11.2023
Newborn babies at risk from bacteria commonly carried by mothers
Newborn babies at risk from bacteria commonly carried by mothers
One in 200 newborns is admitted to a neonatal unit with sepsis caused by a bacteria commonly carried by their mothers - much greater than the previous estimate, say Cambridge researchers. The team has developed an ultra-sensitive test capable of better detecting the bacteria, as it is missed in the vast majority of cases.

Health - Pharmacology - 29.11.2023
New target identified for drugs to treat cancer and age-related diseases
New target identified for drugs to treat cancer and age-related diseases
Insights that pave the way for novel therapeutic approaches to tackle cancer, fibrosis, and many age-related conditions have been uncovered by a team of scientists, including researchers from UCL. The research, published in Nature Cell Biology and led by the Laboratory of Medical Sciences (MRC-LMS), identifies a new target for a class of drugs that selectively eliminate cells that are known to provoke inflammation.

Psychology - Health - 28.11.2023
No ’smoking gun’ mental health harm from internet: landmark Oxford survey
Study of two million individuals' psychological well-being from 2005 to 2022 in 168 countries, in relation to country-level internet-use and mobile broadband statistics Negative and positive experiences had increased on average, but little to no evidence suggesting (mobile) internet use was associated with these changes Links between internet adoption and psychological well-being are small at most, despite popular assumptions about the negative

Health - Pharmacology - 27.11.2023
Early-stage stem cell therapy trial shows promise for treating progressive MS
An international team has shown that the injection of a type of stem cell into the brains of patients living with progressive multiple sclerosis (MS) is safe, well tolerated and has a long-lasting effect that appears to protect the brain from further damage.

Health - Pharmacology - 24.11.2023
Prostate cancer focal therapy is cost effective and may improve patient outcomes
Minimally invasive focal therapies for prostate cancer are associated with a lower overall cost and improved quality of life for patients. These are the findings of a new study , published recently in the Journal of Medical Economics, and led by researchers from Imperial College London. It shows that when compared to surgery or radiotherapy, focal therapies for prostate cancer such as cryotherapy and High Intensity Focused Ultrasound (HIFU) are associated with a lower overall cost and improved quality of life.

Health - 24.11.2023
Premature death of autistic people in the UK investigated for the first time
A new study led by UCL researchers confirms that autistic people experience a reduced life expectancy, however the number of years of life lost may not be as high as previously claimed. The research, published in The Lancet Regional Health - Europe , is the first to estimate the life expectancy and years of life lost by autistic people living in the UK.

Health - Pharmacology - 23.11.2023
Study links deprivation with risk of dying from sepsis
The most socioeconomically deprived groups in society are nearly twice as likely to die from sepsis within 30 days, researchers from The University of Manchester have found. The study of NHS data analysed 248,767 cases of non-COVID-19 sepsis from January 2019, to June, 2022 matched with 1,346,166 controls.

Pharmacology - Health - 21.11.2023
Clinical trial results give new hope for children with rare gliomas
Clinical trial results give new hope for children with rare gliomas
A collaboration of researchers, led by UCL and Great Ormond Street Hospital, have published successful results from a Phase II clinical trial for the treatment of BRAF mutated low-grade paediatric gliomas. Gliomas are cancerous brain tumours that start in glial cells - the supporting cells of the brain.

Life Sciences - Health - 21.11.2023
Our brains are not able to 'rewire' themselves, despite what most scientists believe, new study argues
Our brains are not able to ’rewire’ themselves, despite what most scientists believe, new study argues
Contrary to the commonly-held view, the brain does not have the ability to rewire itself to compensate for the loss of sight, an amputation or stroke, for example, say scientists from the University of Cambridge and Johns Hopkins University.