Results 81 - 100 of 846.

Health - Pharmacology - 08.11.2023
Artificial bladders shine light on bugs that cause urinary tract infections
Artificial bladders shine light on bugs that cause urinary tract infections
A new study led by UCL researchers reveals that numerous bacterial strains are capable of hiding in the human bladder wall, suggesting why urinary tract infections often persist after treatment. The research, published today in Science Advances , is the first to use a sophisticated human tissue model to explore the interaction between host and pathogen for six common species that cause urinary tract infections.

Health - Pharmacology - 01.11.2023
Cancer drug could hold hope for treating inflammatory diseases including gout and heart diseases
A cancer drug currently in the final stages of clinical trials could offer hope for the treatment of a wide range of inflammatory diseases, including gout, heart failure, cardiomyopathy, and atrial fibrillation, say scientists at the University of Cambridge.

Health - Pharmacology - 30.10.2023
Protein interaction causing rare but deadly vaccine-related clotting found
Discovery means potential protective treatments could be developed to block thrombosis from developing following vaccination. A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.

Health - Pharmacology - 27.10.2023
Trial results give hope to patients with severe eye condition
Trial results give hope to patients with severe eye condition
University of Southampton researchers have played a key role in the trial of a potential new treatment for a severe eye disease. Acanthamoeba keratitis (AK) is a rare parasitic infectious disease of the eye, most frequently affecting individuals who wear disposable contact lenses. It causes the front surface of the eye, the cornea, to become painful and inflamed due to infection by Acanthamoeba - a cyst-forming microorganism.

Pharmacology - Psychology - 25.10.2023
Simple blood test can help diagnose bipolar disorder
Simple blood test can help diagnose bipolar disorder
Researchers have developed a new way of improving diagnosis of bipolar disorder that uses a simple blood test to identify biomarkers associated with the condition. The ability to diagnose bipolar disorder with a simple blood test could ensure that patients get the right treatment the first time Jakub Tomasik The researchers, from the University of Cambridge, used a combination of an online psychiatric assessment and a blood test to diagnose patients with bipolar disorder, many of whom had been misdiagnosed with major depressive disorder.

Health - Pharmacology - 25.10.2023
Statin benefits patients with severe COVID-19 while vitamin C is ’ineffective’
A common cholesterol-lowering drug may improve outcomes for critically ill patients with COVID-19, while high dose vitamin C is ineffective. These are the latest findings to come from the REMAP-CAP study, the world's largest trial of multiple interventions for critically ill adults with COVID-19, led by Imperial College London and the Intensive Care National Audit & Research Centre (ICNARC) in the UK.

Health - Pharmacology - 19.10.2023
Surgery-free brain stimulation could provide new treatment for dementia
Surgery-free brain stimulation could provide new treatment for dementia
A new form of deep brain stimulation offers hope for an alternative treatment option for dementia, without the need for surgery. Scientists at Imperial College London are leading on the development and testing of the new method of stimulating the brain, which could provide an alternative treatment for brain diseases such as Alzheimer's, and its associated memory loss.

Health - Pharmacology - 17.10.2023
Novel blood test identifies biomarkers in patients with Alzheimer’s Disease
PD2YXR Scientist viewing a multi well plate containing blood samples for screening a laboratory Study confirms ALZmetrixTM whole blood test can detect people at high risk of developing full Alzheimer's Disease Early results from PharmaKure, a pharmaceutical company spun out from The University of Manchester, shows a novel whole blood test developed by the company is able to quantify Alzheimer's Disease biomarkers.

Pharmacology - Health - 17.10.2023
Amitriptyline helps relieve IBS symptoms
A cheap and widely available prescription drug can improve symptoms of irritable bowel syndrome (IBS) in patients seen in GP surgeries, according to new research led by the universities of Southampton and Leeds. Amitriptyline, which is commonly used at low doses for a range of health concerns, has been found to improve irritable bowel syndrome (IBS) symptoms too, according to the results of the ATLANTIS trial.

Health - Pharmacology - 12.10.2023
Tackling persistent inequities underlying maternal mortality
The MBRRACE-UK collaboration , co-led by Oxford Population Health's National Perinatal Epidemiology Unit , has published the full Saving Lives, Improving Mothers' Care report on women who died during, or up to a year after, pregnancy between 2019 and 2021. The data from this report were published by the collaboration in May 2023.

Health - Pharmacology - 10.10.2023
Wearable sensors provide early detection of progression in Parkinson’s Disease
A team of researchers from the University of Oxford has shown for the first time that it is possible to track the progression of Parkinson's Disease accurately using specially trained machine learning algorithms to analyse data derived from sensor devices worn by patients. The novel methods described in this study led by Professor Chrystalina Antoniades in Oxford's Nuffield Department of Clinical Neurosciences can be used by clinicians alongside the more traditional clinical rating scales to not only improve the accuracy of diagnosis, but also track progression of Parkinson's Disease.

Health - Pharmacology - 06.10.2023
Vulnerability to different COVID-19 mutations depends on previous infections and vaccination
Vulnerability to different COVID-19 mutations depends on previous infections and vaccination
A person's immune response to variants of SARS-CoV-2, the virus that causes COVID-19, depends on their previous exposure - and differences in the focus of immune responses will help scientists understand how to optimise vaccines in the future to provide broad protection. It was a surprise how much of a difference we saw in the focus of immune responses of different people to SARS-CoV-2.

Pharmacology - Health - 04.10.2023
Antibiotics offer no benefit in treating dogs with diarrhoea
Last Updated: 04 Oct 2023 19:00:35 A new VetCompass study from the Royal Veterinary College (RVC) has revealed that veterinary prescription of antibiotics at first presentation of uncomplicated diarrhoea in dogs causes no difference in clinical resolution of these cases. The study suggests that dogs with uncomplicated diarrhoea do not need antibiotics as part of their veterinary care plans.

Health - Pharmacology - 26.09.2023
Fluorescence gives doctors a real-time connection with the health of the gut
Fluorescence gives doctors a real-time connection with the health of the gut
Imperial and US medical technology company MediBeacon have partnered to advance a non-invasive method of assessing intestinal health. In healthy people, the wall of the intestine forms a barrier between the contents of the gut and the rest of the body, with only the nutrients produced by digestion passing through.

Health - Pharmacology - 25.09.2023
New vaccine technology could protect from future viruses and variants
Studies of a 'future-proof' vaccine candidate have shown that just one antigen can be modified to provide a broadly protective immune response in animals. The studies suggest that a single vaccine with combinations of these antigens - a substance that causes the immune system to produce antibodies against it - could protect against an even greater range of current and future coronaviruses.

Health - Pharmacology - 25.09.2023
Widely-used COVID-19 antiviral could be helping SARS-CoV-2 to evolve
Widely-used COVID-19 antiviral could be helping SARS-CoV-2 to evolve
Molnupiravir, an antiviral drug used to treat patients with COVID-19, appears to be driving SARS-CoV-2 to mutate and evolve, with some of these new viruses being transmitted onwards, a new study has shown. It is not clear, however, whether these mutated viruses pose an increased risk to patients or are able to evade the vaccine.

Life Sciences - Pharmacology - 25.09.2023
Brain imaging tool falls short for human tissue
A common research tool used to measure brain inflammation and test new dementia drugs may not be as helpful as scientists had hoped. In clinical research, scientists use a type of imaging called positron emission tomography (PET) to gain a detailed view of what's happening in the brain. One of the markers targeted by scans, called translocator protein (TSPO), has long been used to measure inflammation driven by microglia - the specialised immune cells in the brain which respond to damage and disease.

Pharmacology - Health - 22.09.2023
AI model aims to predict how medicines taste
AI model aims to predict how medicines taste
A team from the UCL Global Business School for Health (GBSH) and the UCL School of Pharmacy are using data collected from an "electric tongue" to create an AI model for predicting the bitterness of drugs. Taste is key to making sure people regularly take their medications and is an important part of drug development.

Pharmacology - 18.09.2023
Portable device instantly detects illegal drugs with 95% accuracy
Portable device instantly detects illegal drugs with 95% accuracy
An ultraportable, low-cost device invented by researchers at the University of Bath proves highly successful at detecting the street drug Spice. Published on Monday 18 September 2023 Last updated on Tuesday 26 September 2023 A device that lights up in the presence of illegal drugs soaked into paper or fabric is expected to be cleared for rollout across the UK over the next few months.

Health - Pharmacology - 12.09.2023
Health of young people with ulcerative colitis at risk due to ceasing medication
Nearly 70 per cent of adolescents and young adults with ulcerative colitis stop taking medication to treat the disease within a year of diagnosis. Ulcerative colitis is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the intestine, and it affects around 200,000 people in the UK.