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Health - Pharmacology - 13.04.2023 
How cancer cells muscle their way into other organs
The biomechanics of how cancer cells escape from the bloodstream to invade other organs has been described for the first time by researchers from UCL, MIT and their collaborators The study, published in Advanced Science , found that the more porous and the softer the tissue, the more likely cancer cells were to force their way in and were able to do so more quickly, providing valuable data for research seeking to prevent or halt cancer metastasis, which is the leading cause of cancer mortality.
Health - Pharmacology - 05.04.2023
Pharmacology - Health - 04.04.2023
Health - Pharmacology - 30.03.2023
Health - Pharmacology - 29.03.2023 
The COVID-19 pandemic has increased - but also polarised - trust in science
Research shows trust in science is more important than knowledge, when it comes to affecting behaviours and attitudes towards science. Research by the Milner Centre for Evolution at the University of Bath, UK, along with colleagues at Universities of Oxford and Aberdeen, finds that trust in scientists has hugely increased overall since the COVID-19 pandemic, but that attitudes have also become more polarized.
Health - Pharmacology - 23.03.2023
Pharmacology - Health - 23.03.2023
Life Sciences - Pharmacology - 21.03.2023 
Advanced brain imaging study hints at how DMT alters perception of reality
Scientists have gleaned new insights into how psychedelics alter conscious experience via their action on brain activity. In a study at Imperial College London, detailed brain imaging data from 20 healthy volunteers revealed how the potent psychedelic compound, DMT (dimethyltryptamine), alters brain function.
Health - Pharmacology - 20.03.2023 
Underactive immune response may explain obesity link to COVID-19 severity
Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists. During the pandemic, the majority of younger patients I saw on the COVID wards were obese. I would have said that it was most likely due to excessive inflammation.
Health - Pharmacology - 13.03.2023
Pharmacology - Health - 13.03.2023
Health - Pharmacology - 06.03.2023 
Reluctance to prescribe medication risks the health of pregnant women
An unwillingness among healthcare professionals to prescribe and dispense otherwise recommended medications is putting the health and lives of pregnant women at risk, finds a new study involving a UCL researcher. The research, published in BMJ Open and involving researchers at UCL, the Centre for Reproductive Research & Communication at BPAS, Cardiff University, and Pregnancy Sickness Support, highlights the experiences of women whose pharmacists had refused to dispense prescriptions made by their GP.
Health - Pharmacology - 02.03.2023
Health - Pharmacology - 01.03.2023
Health - Pharmacology - 22.02.2023 
Analysis: Three in five long COVID patients have organ damage a year after infection
Professor Amitava Banerjee (UCL Institute of Health Informatics) describes in The Conversation his team's recent research finding that 59 percent of long Covid patients suffered organ damage, even in individuals with less-severe initial infections. The latest data from the Office for National Statistics suggests that more than 1.2 million people in the UK report living with long COVID for 12 months or more.
Health - Pharmacology - 21.02.2023 
First heart patients diagnosed using new fibre optic technology
A new diagnostic technology, developed by scientists at UCL, that uses tiny fibre optic sensors to detect the causes of heart disease, more quickly and accurately than existing methods, has been used for the first time in patients. The iKOr device uses an ultra-thin microcatheter integrated with fibre optic sensors and allows doctors to check both blood pressure and blood flow around the heart and look for signs of narrowing and thickening of the arteries - a common sign of disease.
Pharmacology - Health - 16.02.2023
Health - Pharmacology - 13.02.2023 
Conundrum solved over HPV link with head and neck cancer
International analysis has found that discordant results between two types of HPV test linked with worse outcomes for patients Patients who have head and neck cancer caused by the human papilloma virus should be double tested, after new research solves puzzle over worsening outcomes among some people.
Pharmacology - Psychology - 08.02.2023
Life Sciences - Pharmacology - 04.02.2023 
Artificial Intelligence to personalise cancer patient treatments
Sussex researchers use Artificial Intelligence to personalise cancer patient treatments Researchers at the University of Sussex are using Artificial Intelligence (AI) technology to analyse different types of cancer cells to understand different gene dependencies, and to identify genes that are critical to a cell's survival.
Pharmacology
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The biomechanics of how cancer cells escape from the bloodstream to invade other organs has been described for the first time by researchers from UCL, MIT and their collaborators The study, published in Advanced Science , found that the more porous and the softer the tissue, the more likely cancer cells were to force their way in and were able to do so more quickly, providing valuable data for research seeking to prevent or halt cancer metastasis, which is the leading cause of cancer mortality.
Blood differences in long Covid patients
New research has found molecular signature differences in the blood of patients who fully recover from Covid-19 and those who develop long Covid. The study, which involved Cardiff University, examined blood samples from Covid-19 patients at different stages of the disease, including early stages and patients with long Covid.
New research has found molecular signature differences in the blood of patients who fully recover from Covid-19 and those who develop long Covid. The study, which involved Cardiff University, examined blood samples from Covid-19 patients at different stages of the disease, including early stages and patients with long Covid.
GP burnout linked to higher opioid and antibiotic prescribing in England
Burnout in GPs has been linked to higher antibiotic and strong opioid prescribing, especially in the more deprived areas of the North of England, finds research funded by a National Institute for Health and Care Research (NIHR) centre based at The University of Manchester. The study, published in the British Journal of General Practice links the prescribing behaviour of GPs to signs of burnout such as emotional exhaustion, feeling detached from colleagues and patients, lower job dissatisfaction, working longer hours and intentions to leave your job.
Burnout in GPs has been linked to higher antibiotic and strong opioid prescribing, especially in the more deprived areas of the North of England, finds research funded by a National Institute for Health and Care Research (NIHR) centre based at The University of Manchester. The study, published in the British Journal of General Practice links the prescribing behaviour of GPs to signs of burnout such as emotional exhaustion, feeling detached from colleagues and patients, lower job dissatisfaction, working longer hours and intentions to leave your job.
Strong evidence that AAV2 and underlying genetic predisposition played a key role in child hepatitis cases
There is now strong evidence that the virus AAV2, alongside an underlying genetic predisposition, played a key role in cases of acute hepatitis in children, according to a new study published in Nature - the first detailed research investigation into the worldwide outbreak.
There is now strong evidence that the virus AAV2, alongside an underlying genetic predisposition, played a key role in cases of acute hepatitis in children, according to a new study published in Nature - the first detailed research investigation into the worldwide outbreak.
Research shows trust in science is more important than knowledge, when it comes to affecting behaviours and attitudes towards science. Research by the Milner Centre for Evolution at the University of Bath, UK, along with colleagues at Universities of Oxford and Aberdeen, finds that trust in scientists has hugely increased overall since the COVID-19 pandemic, but that attitudes have also become more polarized.
Any type of hormonal contraceptive may increase risk of breast cancer
An analysis of data by researchers at Oxford Population Health's Cancer Epidemiology Unit has shown that use of progestogen-only hormonal contraceptives is associated with a 20-30% higher risk of breast cancer. The results are published in PLOS Medicine . Previous studies have shown that use of the combined contraceptive pill, which combines oestrogen and progestogen, is associated with a small increase in the risk of developing breast cancer that declines after stopping use.
An analysis of data by researchers at Oxford Population Health's Cancer Epidemiology Unit has shown that use of progestogen-only hormonal contraceptives is associated with a 20-30% higher risk of breast cancer. The results are published in PLOS Medicine . Previous studies have shown that use of the combined contraceptive pill, which combines oestrogen and progestogen, is associated with a small increase in the risk of developing breast cancer that declines after stopping use.
Preventing cancer relapse with a genetic test
Date Scientists have found a new way to predict which myeloma patients will benefit the most from a treatment often used to help keep the blood cancer from coming back after a stem cell transplant. For people with certain high-risk genetic features in their cancer cells, the drug, called lenalidomide, cut their risk of seeing their cancer progress or dying by up to 40-fold.
Date Scientists have found a new way to predict which myeloma patients will benefit the most from a treatment often used to help keep the blood cancer from coming back after a stem cell transplant. For people with certain high-risk genetic features in their cancer cells, the drug, called lenalidomide, cut their risk of seeing their cancer progress or dying by up to 40-fold.
Scientists have gleaned new insights into how psychedelics alter conscious experience via their action on brain activity. In a study at Imperial College London, detailed brain imaging data from 20 healthy volunteers revealed how the potent psychedelic compound, DMT (dimethyltryptamine), alters brain function.
Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists. During the pandemic, the majority of younger patients I saw on the COVID wards were obese. I would have said that it was most likely due to excessive inflammation.
Test for spiking to reduce psychological distress
A review of the evidence into the psychological impacts of spiking highlights that victims of suspected attacks are not routinely tested for drugs or alcohol. More should be done to help victims of suspected spiking attacks process the psychological trauma of the event by testing patients who arrive in hospital intoxicated by drink or drunks, say the authors of a new study.
A review of the evidence into the psychological impacts of spiking highlights that victims of suspected attacks are not routinely tested for drugs or alcohol. More should be done to help victims of suspected spiking attacks process the psychological trauma of the event by testing patients who arrive in hospital intoxicated by drink or drunks, say the authors of a new study.
New drug to lower brain pressure could treat blinding IIH headaches, trial finds
Phase two trial saw significant reduction in pressure in the brain and monthly headaches Patients with 'blinding' headaches known as Idiopathic Intercranial Hypertension (IIH) could be treated with an injectable peptide used for type 2 diabetes, a new trial has found. The study, published in the journal Brain , today reports on a phase two trial of a drug called exenatide, a GLP-1 receptor agonist, as a potential treatment for IIH.
Phase two trial saw significant reduction in pressure in the brain and monthly headaches Patients with 'blinding' headaches known as Idiopathic Intercranial Hypertension (IIH) could be treated with an injectable peptide used for type 2 diabetes, a new trial has found. The study, published in the journal Brain , today reports on a phase two trial of a drug called exenatide, a GLP-1 receptor agonist, as a potential treatment for IIH.
An unwillingness among healthcare professionals to prescribe and dispense otherwise recommended medications is putting the health and lives of pregnant women at risk, finds a new study involving a UCL researcher. The research, published in BMJ Open and involving researchers at UCL, the Centre for Reproductive Research & Communication at BPAS, Cardiff University, and Pregnancy Sickness Support, highlights the experiences of women whose pharmacists had refused to dispense prescriptions made by their GP.
Genetic test could guide use of cancer chemotherapy
A genetic test already used routinely in the NHS can guide the use of chemotherapy in people with bowel cancer, new research has shown. Researchers from Imperial College London, the Institute of Cancer Research (ICR) and the Netherlands Cancer Institute , found that the test can predict whether a bowel cancer patient will benefit from chemotherapy.
A genetic test already used routinely in the NHS can guide the use of chemotherapy in people with bowel cancer, new research has shown. Researchers from Imperial College London, the Institute of Cancer Research (ICR) and the Netherlands Cancer Institute , found that the test can predict whether a bowel cancer patient will benefit from chemotherapy.
Women’s health at risk from reluctance to prescribe medicine during pregnancy
Research has found that a reluctance among healthcare professionals to prescribe and dispense medications to women who are pregnant is placing their health at risk. The study conducted by researchers at the British Pregnancy Advisory Service, Cardiff University, Pregnancy Sickness Support, and University College London, found that while prescribers need to balance maternal benefit with potential foetal harm when prescribing in pregnancy, women's individual circumstances were not always considered, and they were not fully engaged in decision making.
Research has found that a reluctance among healthcare professionals to prescribe and dispense medications to women who are pregnant is placing their health at risk. The study conducted by researchers at the British Pregnancy Advisory Service, Cardiff University, Pregnancy Sickness Support, and University College London, found that while prescribers need to balance maternal benefit with potential foetal harm when prescribing in pregnancy, women's individual circumstances were not always considered, and they were not fully engaged in decision making.
Professor Amitava Banerjee (UCL Institute of Health Informatics) describes in The Conversation his team's recent research finding that 59 percent of long Covid patients suffered organ damage, even in individuals with less-severe initial infections. The latest data from the Office for National Statistics suggests that more than 1.2 million people in the UK report living with long COVID for 12 months or more.
A new diagnostic technology, developed by scientists at UCL, that uses tiny fibre optic sensors to detect the causes of heart disease, more quickly and accurately than existing methods, has been used for the first time in patients. The iKOr device uses an ultra-thin microcatheter integrated with fibre optic sensors and allows doctors to check both blood pressure and blood flow around the heart and look for signs of narrowing and thickening of the arteries - a common sign of disease.
Pharmacists based in care homes make them safer for residents
Basing specialist pharmacists in care homes can help make residents safer by cutting potential harm from medicines, according to research carried out by University of Leeds academics. The Care Home Independent Pharmacist Prescriber Study (CHIPPS), which involved researchers in Leeds and across the country, trialled onsite pharmacists in dozens of care homes.
Basing specialist pharmacists in care homes can help make residents safer by cutting potential harm from medicines, according to research carried out by University of Leeds academics. The Care Home Independent Pharmacist Prescriber Study (CHIPPS), which involved researchers in Leeds and across the country, trialled onsite pharmacists in dozens of care homes.
International analysis has found that discordant results between two types of HPV test linked with worse outcomes for patients Patients who have head and neck cancer caused by the human papilloma virus should be double tested, after new research solves puzzle over worsening outcomes among some people.
Cannabis has same effect on adolescents and adults, and CBD doesn’t dampen effects
The short-term effects of vaporised cannabis do not differ between adolescents and adults, while cannabidiol (CBD) does not dampen the effects of the drug, finds a new study led by UCL and King's College London researchers. For the experimental study published in Addiction , the researchers measured how regular cannabis users of different ages responded to inhaling cannabis with differing levels of CBD.
The short-term effects of vaporised cannabis do not differ between adolescents and adults, while cannabidiol (CBD) does not dampen the effects of the drug, finds a new study led by UCL and King's College London researchers. For the experimental study published in Addiction , the researchers measured how regular cannabis users of different ages responded to inhaling cannabis with differing levels of CBD.
Sussex researchers use Artificial Intelligence to personalise cancer patient treatments Researchers at the University of Sussex are using Artificial Intelligence (AI) technology to analyse different types of cancer cells to understand different gene dependencies, and to identify genes that are critical to a cell's survival.
