Results 21 - 40 of 851.

Health - Pharmacology - 01.05.2024
Immune cells hunt down cancer around the body
Scientists have discovered the key features of immune B cells which make them successful at targeting tumours - including when cancer has spread to a different part of the body. Published in Nature Immunology , the researchers have developed a computational tool to identify these anti-cancer immune cells which could lead to improved, personalised immunotherapies.

Health - Pharmacology - 01.05.2024
Liver study pinpoints cell that helps healing process
A type of cell responsible for repairing damaged liver tissue has been uncovered for the first time by a team of scientists, including Professor Rajiv Jalan (UCL Liver & Digestive Health). The study, published in Nature , showed how these new-found cells migrate to the site of damage, providing new insights into the way the liver heals itself.

Health - Pharmacology - 29.04.2024
Exercise programmes benefit a wide range of long-term health conditions
A new study looking at health data from the last 20 years has highlighted the benefits of exercise programmes for individuals living with long-term health conditions. Drawing on a comprehensive overview of published evidence spanning 39 different long-term conditions - and encompassing 990 randomised controlled trials and over 900,000 patients - the research underscores the fundamental role of exercise in enhancing the wellbeing of individuals living with long-term health conditions.

Health - Pharmacology - 26.04.2024
New treatment for brain tumours approved following decades of work
The first ever targeted treatment for brain tumours in children has been approved for NHS patients, following over 20 years of research by a UCL clinician scientist. Professor Darren Hargrave, who is a researcher at the UCL Great Ormond Street Institute of Child Health and consultant at Great Ormond Street Hospital for Children (GOSH), was the Chair of the TADPOLE-G trial steering group, alongside researchers across the world.

Health - Pharmacology - 26.04.2024
Azithromycin and preventing chronic lung disease in premature babies
The early use of azithromycin does not prevent the development of chronic lung disease in premature babies, finds new research by Cardiff University. The largest clinic trial for azithromycin and chronic lung diseases in premature babies has provided definitive answers to whether azithromycin can decrease rates of chronic lung disease in prematurely born babies.

Health - Pharmacology - 19.04.2024
Training AI models to answer ’what if’’ questions could improve medical treatments
Machines can learn not only to make predictions, but to handle causal relationships. An international research team shows how this could make medical treatments safer, more efficient, and more personalised. Artificial intelligence techniques can be helpful for multiple medical applications, such as radiology or oncology, where the ability to recognise patterns in large volumes of data is vital.

Pharmacology - Health - 17.04.2024
Antipsychotics for dementia linked to more harms than previously acknowledged
Risks highest soon after starting drugs, underscoring need for increased caution in early stages of treatment, say experts Antipsychotic use in people with dementia is associated with higher risks of a wide range of serious health outcomes compared with non-use, according to a new study from a collaboration across the Universities of Manchester, Nottingham, Edinburgh and Dundee.

Health - Pharmacology - 08.04.2024
Long COVID leaves telltale traces in the blood
People with long COVID have distinct patterns of inflammation detectable in the blood, which could potentially be targeted with immune therapies. Findings from the largest UK study of patients hospitalised with SARS-CoV-2 infection show that long COVID leads to ongoing inflammation which can be detected in the blood.

Chemistry - Pharmacology - 08.04.2024
Cutting-edge ruthenium catalyst for new reaction discovery and optimisation
Researchers at The University of Manchester have achieved a groundbreaking advancement in catalyst technology. They have developed a new catalyst which has been shown to have a wide variety of uses and the potential to streamline optimisation processes in industry and support new scientific discoveries.

Pharmacology - Health - 01.04.2024
New synthesis platform allows for rapid cancer drug synthesis and testing
New synthesis platform allows for rapid cancer drug synthesis and testing
Researchers have developed a new platform for the synthesis, analysis and testing of new compounds which may one day treat cancer The discovery of new compounds with pharmacological properties can be expensive and time-consuming. Therefore, there is an increasing interest in developing workflows that allow for the rapid synthesis and testing of multiple compounds in parallel.

Health - Pharmacology - 28.03.2024
TB vaccine may enable elimination of the disease in cattle by reducing its spread
Vaccination not only reduces the severity of TB in infected cattle, but reduces its spread in dairy herds by 89%, research finds. Our study suggests that vaccination not only reduces the progression of the disease, but that if vaccinated animals become infected, they are substantially less infectious to others.

Psychology - Pharmacology - 27.03.2024
People with depression see no immediate change from common GP assessment
People with depression see no immediate change from common GP assessment
But PHQ-9 questionnaire used to monitor primary care patients did reveal benefits across six months A commonly used questionnaire adopted by GPs to monitor the treatment of depression does not provide any immediate benefits to patients, a new study has found. Primary care researchers testing the PHQ-9 assessment, which measures the severity of depression, found it did nothing to improve people's symptoms after 12 weeks.

Health - Pharmacology - 27.03.2024
Locums and permanent GPs equally safe, study reassures patients
There is no evidence that locum doctors are less clinically competent or practice less safely than permanent doctors, a study in England led by University of Manchester researchers has shown. Some differences in practice and performance of locum and permanent GPs were found, however the researchers suggest they are likely to be shaped by the organisational setting and systems within which they work.

Pharmacology - Health - 26.03.2024
Clinical trial shows rheumatoid arthritis drug could prevent disease
A drug used to treat rheumatoid arthritis could also prevent the disease in individuals deemed to be at risk. Results from a Phase 2b clinical trial, published in The Lancet by a team led by King's College London and involving Birmingham researchers, provides hope for arthritis sufferers after it showed that the biologic drug abatacept reduces progression to this agonising chronic inflammatory disease.

Health - Pharmacology - 21.03.2024
Kinder test could improve diagnosis of womb cancer
A simple, safe and accurate test that identifies women with womb cancer from a sample taken from the vagina has been developed by clinician scientists from The University of Manchester. The research, published in the journal Ebiomedicine, part of the Lancet Discovery Science, reports that the test has over 95% accuracy in identifying post-menopausal women with cancer as the cause of their bleeding, and is more accurate than current methods.

Health - Pharmacology - 18.03.2024
New research could help doctors ’see’ bowel cancer
Imaging technology could provide a ground-breaking new approach for diagnosing and treating bowel cancer patients, thanks to Cancer Research scientists in Glasgow. Biopsies are currently used to diagnose bowel cancer but require an invasive procedure which offers risks, such as potential infection, and are unable to capture an entire picture of what is happening in a patient's bowel.

Health - Pharmacology - 18.03.2024
New blood test could identify people at highest risk of dying from heart failure
A blood test could help identify those at highest risk of dying from heart failure, new research has found. The study, funded by the British Heart Foundation, found that patients with highest levels of a protein called neuropeptide Y (NPY) were 50 per cent more likely to die from a heart complication over the three years that the research was conducted, compared to those with lower levels.

Health - Pharmacology - 14.03.2024
Treatments for rare diseases are needed to beat kidney failure
Treatments for rare diseases are needed to beat kidney failure
Focusing on rare conditions could significantly reduce the burden of kidney disease on both patients and the NHS, according to a major new study led by UCL and the UK Kidney Association. The study, published in The Lancet to mark World Kidney Day, draws on the largest rare kidney disease dataset ever created.

Health - Pharmacology - 11.03.2024
Antimalarial treatments more likely to fail in children with acute malnutrition
Children with acute malnutrition across Africa and Asia have a higher risk of treatment failure and malaria reinfection, even after being given the best currently available and recommended malaria treatment. Researchers from the Infectious Diseases Data Observatory (IDDO) at Oxford University analysed data from over 11,000 young children for this study, published in Lancet Global Health .

Health - Pharmacology - 11.03.2024
New prostate cancer treatments could reach men sooner
New prostate cancer treatments could reach men sooner
A new study involving UCL researchers has found that better prostate cancer treatments could reach men almost two years earlier than is currently possible. Currently, it takes around 10 years for new treatments to be studied in large-scale trials. However, the new research showed that the length of time a man lives without his cancer progressing - known as progression-free survival - reasonably predicts how long he will eventually live ('overall survival').