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Pharmacology - Health - 16.01.2020
Cheap roundworm drug found to enhance the effects of chemotherapy in prostate cancer
Scientists at the University of Glasgow and Cancer Research UK Beatson Institute have tested close to 1000 existing medicines and discovered that a cheap drug commonly used to treat parasitic worm infection could be a game-changing treatment for prostate cancer. Prostate cancer is the most common cancer affecting men and the second most common cause of cancer death for men in the UK.

Social Sciences - Health - 16.01.2020
Lifetime suicide risk factors identified
A new review of previous studies into suicide worldwide has highlighted the effects of individual and environmental risk factors over a lifetime.

Pharmacology - Health - 16.01.2020
Patients needed for irritable bowel syndrome trial
Patients needed for irritable bowel syndrome trial
Patients in GP surgeries in Bristol are being invited to take part in a large trial of low-dose amitriptyline for irritable bowel syndrome (IBS) lead by researchers from the universities of Bristol, Leeds and Southampton. IBS is a common gut disorder affecting one in ten people. Abdominal pain, bloating, and altered bowel habit affect patients' quality of life substantially and can force them to take days off work.

Health - 15.01.2020
Obesity crisis blamed for a rise in fatty liver disease amongst young adults
Obesity crisis blamed for a rise in fatty liver disease amongst young adults
One in five young people have fatty liver disease (steatosis), with one in 40 having already developed liver scarring (fibrosis), research published today [15 January] has found. The study, published in The Lancet Gastroenterology & Hepatology, is the first to attempt to determine the prevalence of fatty liver disease and fibrosis in young healthy adults in the UK.

Health - Life Sciences - 15.01.2020
Into leading cause of stillbirth awarded 2.4 million funding
Researchers have been awarded over £2.4 million to investigate the best technique to manage poor growth in babies during the later stages of pregnancy Fetal growth restriction (FGR) can lead to stillbirth, accounting for half of the cases of stillbirth in the UK. The new international study, funded by the National Institute for Health Research (NIHR), will investigate the best time to deliver babies who are diagnosed with FGR in late preterm pregnancy.

Pharmacology - Health - 15.01.2020
Stepping up to the challenge: studying drug dosage during an Ebola outbreak
A specialist technique used to study drugs has been completed for the first time during an outbreak of Ebola virus disease. The study published today in eBiomedicine was a collaboration of researchers from Sierra Leone and the University's of Glasgow, Oxford, Cambridge and the Liverpool School of Tropical Medicine.

Health - Psychology - 15.01.2020
Miscarriage and ectopic pregnancy may trigger long-term post-traumatic stress
Miscarriage and ectopic pregnancy may trigger long-term post-traumatic stress
One in six women experience long-term post-traumatic stress following miscarriage or ectopic pregnancy. This is the finding of the largest ever study into the psychological impact of early-stage pregnancy loss, from scientists at Imperial College London and KU Leuven in Belgium. Pregnancy loss affects up to one in two women, and for many women it will be the most traumatic event in their life.

Health - Life Sciences - 14.01.2020
HIV ’hotspots’ not necessarily major drivers of new infections
Areas of high HIV prevalence, known as 'hotspots', do not necessarily fuel the epidemic in the wider population, say researchers. Hotspots are often targeted for intense HIV control interventions, including treatment and prevention, to maximise their effect and reach the people in greatest need first.

Life Sciences - Health - 14.01.2020
Brain blood flow sensor discovery could aid treatments for dementia
Researchers at UCL have discovered the mechanism that allows the brain to monitor its own blood supply, a finding in rats which may help to find new treatments for conditions including hypertension (high blood pressure) and dementia. For decades, scientists have suspected that the brain had a way of monitoring and regulating its own blood flow separate from the body-wide blood pressure control system, but until now no one had proven this.

Life Sciences - Health - 14.01.2020
Malnutrition linked with increased risk of Zika birth defects
The severity of Zika virus-related deformations in babies has been shown to be affected by environmental factors such as maternal nutrition. Environmental factors, such as the diets of pregnant women, have been shown to have an effect on the extent and severity of developmental malformations in babies associated with Zika virus (ZIKV) congenital infection.

Health - Pharmacology - 14.01.2020
Routine HIV screening in general practice boosts testing and early diagnosis
Offering HIV screening to new patients in general practice on a routine basis increases testing rates and improves detection and earlier diagnosis, according to research co-led by UCL and Queen Mary University of London HIV testing rates in general practice are low, despite testing being recommended in UK and international guidelines.

Life Sciences - Health - 14.01.2020
Lack of key protein reduces brain connections in schizophrenia
Lack of key protein reduces brain connections in schizophrenia
Brain scans have revealed for the first time how people with schizophrenia have reduced levels of a key protein which helps brain cells to communicate The findings, published today , have shown a lack of a protein called SV2A in the brains of those with schizophrenia, compared to those without. According to the researchers who carried out the study, the findings suggest the protein could provide a new target for research into potential treatments.

Health - Life Sciences - 14.01.2020
Long-term skin irritation linked to increased risk of tumour growth
Long-term skin irritation linked to increased risk of tumour growth
An antibody that usually helps defend the skin against harmful substances or infections may promote tumour growth during chronic tissue inflammation. One of the skin's defences against environmental assault can help tumours to grow when skin is exposed to chronic inflammation, finds a study in mice published today in eLife.

Social Sciences - Health - 14.01.2020
Wealth adds nine years to ’healthy’ life expectancy
The wealthiest men and women can expect to live an additional eight to nine years free from disability compared to people in the poorest groups, according to new UCL-led research.

Social Sciences - Health - 13.01.2020
Rising temperatures may cause over 2000 fatal injuries per year in the US
A 2 degrees Celsius rise in temperatures could result in around 2,100 additional deaths from injuries every year in the United States. This is the finding of research from Imperial College London , Columbia University and Harvard University , published Medicine. In the study, funded by the US Environmental Protection Agency and the Wellcome Trust, the researchers calculated the number of additional fatal injuries that would occur in the US if temperatures rose by 1.5 and 2 degrees Celsius.

Life Sciences - Health - 13.01.2020
Researchers identify new genetic link to schizophrenia
Researchers identify new genetic link to schizophrenia
Cardiff University researchers have identified new mutations in a gene that provides novel insights into the biological causes of schizophrenia. Dr Elliott Rees, a research fellow at the Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, analysed genetic data from 3,444 families affected by schizophrenia, in the largest study of its kind.

Life Sciences - Health - 08.01.2020
Key to Iron Age ’Heslington brain’ preservation
The 2,600-year-old Heslington brain, discovered in 2008 near York in the UK, was probably so well-preserved due to tightly folded brain proteins, finds a new UCL-led study. The brain matter was the only soft tissue that remained in the skull, which dated from around 673-482 BCE. The new findings, published in Journal of the Royal Society Interface , suggest that the first few months after the person's death may have been key to the extraordinary degree of brain preservation.

Life Sciences - Health - 08.01.2020
2,600-year-old brain preserved with protein folding
The 2,600-year-old Heslington brain, discovered in 2008 near York in the UK, was likely so well-preserved due to tightly folded brain proteins, finds a new UCL-led study. The brain matter was the only soft tissue that remained in the skull, which dated from around 673-482 BCE. The new findings, published in Journal of the Royal Society Interface , suggest that the first few months after the person's death may have been key to the extraordinary degree of brain preservation.

Health - 07.01.2020
Immune cell discovery opens door to new powerful cancer therapies
Scientists at UCL have identified how a subset of immune cells are activated to kill cancerous cells, a finding in mice which could hold the key to new powerful therapies against cancer. This new study built on previous research*, also led by Professors Sergio Quezada and Karl Peggs (both UCL Cancer Institute), which found that following immunotherapy some CD4+ T cells, traditionally thought to be 'helper' and 'regulator' immune cells, become cytotoxic and directly engage with and kill cancer cells.

Health - Life Sciences - 07.01.2020
Detailed genetic study provides most comprehensive map of risk to date of breast cancer risk
Detailed genetic study provides most comprehensive map of risk to date of breast cancer risk
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