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Pharmacology



Results 61 - 80 of 162.


Health - Pharmacology - 11.09.2019
More die after surgery than from HIV, TB, and malaria combined - study
Around the world 4.2 million people die every year within 30 days after surgery - with half of these deaths occurring in lowand middle-income countries (LMICs), a new study reveals. There is also a significant unmet need for surgery in LMICs and researchers believe that if operations were provided for all patients who need them the number of global post-operative deaths would increase to 6.1 million.

Health - Pharmacology - 10.09.2019
Dietary supplement may help with schizophrenia
A dietary supplement, sarcosine, may help with schizophrenia as part of a holistic approach complementing antipsychotic medication, according to a UCL researcher. In an editorial published in the British Journal of Psychiatry , Professor David Curtis (UCL Genetics, Evolution & Environment and QMUL Centre for Psychiatry) suggests the readily available product could easily be incorporated into treatment plans, while calling for clinical trials to clarify the benefit and inform guidelines.

Health - Pharmacology - 09.09.2019
Blood test shows promise to aid better detection of lung cancer
Lung cancer can be spotted earlier and diagnosed more precisely with the help of a blood test, a major study carried out in Scotland has found. The Early Detection of Cancer of the Lung Scotland (ECLS) is the world's largest clinical biomarker trial looking into detecting early lung cancer using a blood test.

Life Sciences - Pharmacology - 04.09.2019
Protein tangles linked with dementia seen for first time in patients’ brains
Scientists have visualised for the first time protein 'tangles' associated with dementia in the brains of patients who have suffered a single head injury. This is the finding of a new study led by scientists from Imperial College London, published Translational Medicine. In the early-stage study, researchers studied 21 patients who had suffered a moderate to severe head injury at least 18 years earlier (mostly from traffic accidents), as well as 11 healthy individuals who had not experienced a head injury.

Health - Pharmacology - 04.09.2019
Cracking "virus code" could help fight cancer
Virus experts from Cardiff University's School of Medicine have uncovered, for the first time, how a virus known as Adenovirus type 26 (Ad26), which has been used effectively in a tamed form as a vaccine, can infect human cells. Ad26 is a virus of great interest to the scientific and medical community.

Pharmacology - Health - 03.09.2019
Cholesterol-cutting gene silencing treatment shows lasting effects
Twice-yearly injections of a cholesterol-cutting medication could offer patients lasting reduction in cholesterol, cutting risk of heart attacks. A new, currently-unlicensed drug treatment that works by ‘silencing' genes can help to halve levels of LDL cholesterol with just two injections per year, according to new data presented this week.

Health - Pharmacology - 02.09.2019
Breast cancer can form ’sleeper cells’ after drug treatment
Breast cancer medicines may force some cancer cells into 'sleeper mode', allowing them to potentially come back to life years after initial treatment. These are the early-stage findings from scientists at Imperial College London , who studied human breast cancer cells in the laboratory.

Health - Pharmacology - 02.09.2019
Bacteria behind hospital infections block out antibiotics
Drug-resistant bacteria responsible for deadly hospital-acquired infections shut out antibiotics by closing tiny doors in their cell walls. The new finding by researchers at the MRC Centre for Molecular Bacteriology and Infection , Imperial College London, could allow researchers to design new drugs that ‘pick the locks' of these closed doors and allow antibiotics into bacterial cells.

Pharmacology - Health - 01.09.2019
Diabetes medication can be used to treat heart failure
A common diabetes medication, originally introduced as a treatment for diabetes, can be successfully used to treat patients with heart failure, reducing their risk of worsening heart failure or death from cardiovascular causes by more than 25%. The new research, which is presented today at the European Society of Cardiology Congress 2019, found the diabetes drug dapagliflozin could be used as a treatment for patients with heart failure, even if they don't also have diabetes.

Pharmacology - Life Sciences - 29.08.2019
Drug discovery offers new hope to halt the spread of malaria
Drug discovery offers new hope to halt the spread of malaria Breakthrough research has revealed a new drug that may prevent the spread of malaria, and also treat people suffering with the deadly parasitic disease. The findings, which were delivered by an international team of scientists led by the University of Glasgow and published today in Science, offer fresh hope in the global fight against malaria.

Pharmacology - Health - 25.08.2019
Removing cancer’s protective barrier could boost immunotherapy treatments
Scientists at the University of Birmingham may have found a way to pull down the protective wall that surrounds tumours, potentially re-exposing them to the killing power of the immune system and immunotherapy treatments, according to a study part funded by Cancer Research UK and published in EBioMedicine today.

Health - Pharmacology - 23.08.2019
Shows low-cost once a day combination pill can prevent heart disease and stroke
Research carried out in collaboration with the University of Birmingham in the UK has shown a combination low-cost pill called a polypill containing four drugs is effective in preventing cardiovascular disease. The results of the clinical trial, published in The Lancet , demonstrate for the first time the effectiveness of a fixed-dose combination pill for preventing cardiovascular disease (heart disease and stroke) and indicate that the benefits of widespread polypill use outweigh any known side effects.

Pharmacology - Health - 20.08.2019
Aggressive brain tumour could be diagnosed with simple blood test
New research by Sussex scientists could be the first step towards developing a blood test to diagnose the most aggressive type of brain tumour, known as Glioblastoma. A team from Professor Georgios Giamas' lab at the University of Sussex has identified novel biomarkers within bodily fluids, which signal the presence of the tumour.

Pharmacology - Health - 16.08.2019
New tool could lead to improved care of patients living with artificial heart pump
New research led by the University of Birmingham and funded by the British Heart Foundation (BHF) could improve the lives of those living with an artificial heart pump. A left ventricular assist device (LVAD) is a battery-operated, mechanical pump surgically implanted into patients who have end-stage heart failure.

Health - Pharmacology - 16.08.2019
Relaxing of regulations for regenerative medicines has cascading effect internationally, new research warns
Countries that relax regulations for regenerative medicines could be causing a downward spiral in international standards, according to new research published today. Researchers warn that if just one country decides to relax regulations in the field, a heightened sense of competition can spur others to do the same.

Life Sciences - Pharmacology - 15.08.2019
Faulty gene leads to kidney disease
New insights into why a faulty gene involved in a devastating form of a kidney condition called nephrotic syndrome leads to disease in some patients have been identified in new Kidney Research UK-funded research led by the University of Bristol. The findings, published in the Journal of the American Society of Nephrology (JASN), could pave the way for new ways to prevent or treat the condition, by revealing new targets to intervene in the process.

Health - Pharmacology - 15.08.2019
Dog detectives sniff out harmful bacteria causing lung infections
Sniffer dogs have been trained to detect ultra-low concentrations of bacteria which cause lung infection in cystic fibrosis (CF) patients. In a study by Imperial College London and the charity Medical Detection Dogs , researchers found that specially trained medical detection dogs were able to detect ultra-low concentrations of Pseudomonas aeruginosa (Pa), the most common cause of lung infection in people with CF.

Health - Pharmacology - 13.08.2019
MRI assisted biopsies more effective at identifying prostate cancer that needs treatment than standard biopsies
Using MRI scans to target biopsies is more effective at detecting prostate cancers that are likely to need treatment than standard ultrasound guided biopsies alone, according to research published on 7 August in JAMA Network Open. The research, led by the National Institute for Health Research (NIHR) and Universities of Bristol, Ottawa, Exeter and Oxford, combined the results from seven studies covering 2,582 patients.

Pharmacology - Health - 12.08.2019
First vaccine for chlamydia shows promise in early trials
The first ever early clinical trial for a vaccine for genital chlamydia has shown it to be safe and effective at provoking an immune response. The latest findings , from a randomised controlled trial of 35 healthy women led by Imperial College London and the Statens Serum Institut in Copenhagen, demonstrate promising early signs of what could be an effective vaccine against chlamydia.

Life Sciences - Pharmacology - 12.08.2019
Animal welfare and research 3Rs symposium
Scientists had the opportunity to find out about current research and share best practice of the '3Rs': Replace, Reduce and Refine at this year's University of Bristol Animal Welfare and Research 3Rs symposium, held earlier this summer. The principles of 3Rs, developed over 50 years ago as a framework for humane animal research, are fixed in European and UK law.

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