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Pharmacology - Health - 11.12.2019
Up to two fifths of antibiotic prescriptions in the US could be inappropriate
Such a high degree of potentially unnecessary prescribing has important implications for antibiotic stewardship - efforts to reduce antibiotic use in response to the growing threat of antimicrobial resistance. Inappropriate antibiotic prescribing is a major public health problem. Studies examining the appropriateness of antibiotic prescribing rely on a "documented indication" in patients' medical records.

Health - Pharmacology - 09.12.2019
Deeper understanding of irregular heartbeat may lead to more effective treatment
Deeper understanding of irregular heartbeat may lead to more effective treatment
Researchers at Imperial have shown how the chaotic electrical signals underlying irregular heart rhythms lead to the failure of standard treatments. By modelling how electrical signals on the inside and the outside of the heart move across the muscle, researchers at Imperial College London have suggested why corrective surgery is not currently always beneficial.

Health - Pharmacology - 06.12.2019
Patients at risk because NHS hospitals using different record-keeping systems
A major survey of medical record keeping in the NHS has revealed critical deficiencies that could risk patients' safety. Researchers at the Institute of Global Health Innovation (IGHI) at Imperial College London, found NHS Trusts were using at least 21 different electronic medical record systems which are unable to effectively share information.

Pharmacology - Health - 05.12.2019
Reveals dramatic rise in patients ’cured’ of heart condition following GP performance pay scheme
The introduction of a performance-related financial incentive scheme for GPs led to a dramatic almost five-fold rise in the number of patients whose heart rhythm condition was said to have been ‘cured', say University of Birmingham researchers. Academics at the University of Birmingham's Institute of Applied Health Research, supported by NIHR ARC West Midlands, conducted a study into patients with the most common heart rhythm condition, called atrial fibrillation.

Pharmacology - Health - 04.12.2019
Typhoid vaccine over 81% effective in tackling disease in Nepal
Typhoid vaccine over 81% effective in tackling disease in Nepal
A large field study of typhoid conjugate vaccine (TCV) in Nepal has shown a single dose to be safe and effective in reducing typhoid in children aged 9 months to <16 years in an endemic setting. Caused by the bacterium Salmonella Typhi, typhoid is a major cause of fever in children in lowand middle-income countries and is responsible for nearly 11 million cases and more than 116,000 deaths a year worldwide.

Pharmacology - Health - 03.12.2019
One dose of radiotherapy as effective as five doses for cancer in the spine
A single dose of radiotherapy is as "effective" as five doses for end-of-life cancer patients suffering with painful spinal canal compression, finds a large study conducted by UCL. Spinal canal compression is a common complication in cancer patients when the cancer has spread to their spine. Radiotherapy is used to control pain and alleviate symptoms.

Pharmacology - Health - 02.12.2019
Face mask can help combat mild cases of sleep condition
Face mask can help combat mild cases of sleep condition
A night time face mask can improve energy levels and vitality in people who suffer from the condition sleep apnoea. This is the finding from a new study of over 200 patients, published in the journal The Lancet Respiratory Medicine , led by Imperial College London. We are seeing increasing cases of sleep apnoea, and in a wide range of patients.

Health - Pharmacology - 01.12.2019
Highlights obesity services a patient postcode lottery
New research highlights obesity services a patient postcode lottery A lack of consistent reporting on obesity and weight management programmes around the UK, has created a postcode lottery for patient care. Researchers from the University of Glasgow have highlighted the inconsistences in NHS weight management programmes across the UK, in a study published in Obesity Reviews.

Pharmacology - Health - 28.11.2019
Pharmacist-led interventions may help prevent cardiovascular disease
Pharmacists based in GP practices can play an integral role in the prevention of cardiovascular disease, finds new research led by the University of Birmingham. The study findings, published today in the British Journal of Clinical Pharmacology , support the involvement of pharmacists as healthcare providers in managing patients with hypertension, diabetes and high cholesterol.

Pharmacology - Health - 26.11.2019
Doctors should avoid co-prescribing benzodiazepines to opioid dependent patients due to increase in overdose death
Doctors should avoid co-prescribing benzodiazepines to opioid dependent patients who are being treated with methadone or buprenorphine, also known as opioid agonist treatment (OAT), due to a three-fold increase in risk of overdose death, according to a study led by researchers at the University of Bristol.

Pharmacology - Health - 26.11.2019
One shot of ketamine could reduce problem drinking
A one-off dose of ketamine could help heavy drinkers reduce their alcohol intake, finds a new UCL experimental study. Giving a shot of ketamine to heavy drinkers after reactivating their drinking-related memories led to a rapid decrease in urges to drink and a prolonged decrease in alcohol intake over nine months, according to the study published .

Health - Pharmacology - 26.11.2019
One third of UK doctors may suffer from workplace 'burnout'
One third of UK doctors may suffer from workplace ’burnout’
One in three UK doctors working in obstetrics and gynaecology may suffer from workplace burnout. This could affect their well-being and how they treat patients. This is the finding of new research, published in the journal BMJ Open , led by scientists at Imperial College London.

Pharmacology - 21.11.2019
Potential new treatment for rare muscle-wasting disease
Potential new treatment for rare muscle-wasting disease
A team of Cardiff University researchers has uncovered a potential new way to treat a very rare genetic disorder that causes muscles in the arms and legs to become increasingly weak. GNE myopathy is a debilitating condition that affects young adults in their 20s or 30s, typically leaving them in a wheelchair within years.

Pharmacology - Health - 21.11.2019
Small rise in heart attack protein linked to increased risk of early death
An analysis of patients' heart data has shown that even a small increase in a protein linked to heart attacks is linked to an increased risk of death. Clinicians use troponin testing, alongside other investigations, to determine whether a patient is having a heart attack and to inform treatment choices.

Health - Pharmacology - 20.11.2019
New maths reveals how diseases progress and bacteria develop drug resistance
Scientists from Imperial and the University of Bergen have found a new way to predict how a disease will likely progress in individual patients. This could help patients receive more targeted treatments earlier in the progress of their disease. [Our approach] is very useful for tracking disease markers, learning about biological evolution and other processes that occur over time.

Health - Pharmacology - 20.11.2019
Digital sepsis monitoring system helps save lives and improves care
Digital sepsis monitoring system helps save lives and improves care
The introduction of a digital alert system to monitor patients with sepsis has led to a reduction in deaths and hospital stays. Sepsis, also known as blood poisoning, is life threatening and accounts for an estimated 46,000 deaths in the UK each year. If diagnosed early it can be treated effectively with antibiotics but the difficulty lies in spotting sepsis before it develops, as symptoms are similar to other illnesses such as flu.

Health - Pharmacology - 19.11.2019
Technique to preserve sexual function after prostate cancer surgery
A UCLH and UCL led trial of a technique to preserve men's sexual potency after prostate cancer surgery has begun to recruit participants across the UK. The trial of the NeuroSAFE procedure - designed to avoid the removal during surgery of nerves near the prostate which are important for sexual function - is being led by UCLH consultant urological surgeon Greg Shaw and sponsored by UCL.

Life Sciences - Pharmacology - 19.11.2019
Ayahuasca compound changes brainwaves to vivid 'waking-dream' state
Ayahuasca compound changes brainwaves to vivid ’waking-dream’ state
Scientists have peered inside the brain to show how taking DMT affects human consciousness by significantly altering the brain's electrical activity. DMT (or dimethyltryptamine) is one of the main psychoactive constituents in ayahuasca, the psychedelic brew traditionally made from vines and leaves of the Amazon rainforest.

Pharmacology - 18.11.2019
Scientists and schoolkids find family soups have antimalarial properties
London schoolchildren have found that some of their families' soup recipes have antimalarial properties, with the help of Imperial scientists. Researchers from Imperial College London helped the schoolchildren test their family soup broths for activity against the malaria parasite. We may have to look beyond the chemistry shelf for new drugs, and natural remedies shouldn't be off our watch list, as artemisinin shows.

Health - Pharmacology - 18.11.2019
Scientists make vampire bats ’glow’ to simulate vaccine spread
Scientists have used 'glowing' fluorescent gel to estimate the potential effectiveness of spreadable vaccines to control diseases in wild bats. The study - led by researchers at the Universities of Glasgow and Michigan, and published today in Nature Ecology and Evolution - found that a low effort vaccination programme could substantially reduce rabies transmission in wild vampire bats, thereby reducing the risk of lethal infections in humans and livestock.
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