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Research Associate in Synthetic Biology & Enzymology: Discovery and Engineering New Biosynthetic Pathways to Next Generation Antibiotics

Closing Date
WorkplaceManchester, Princess St, North West England, UK


£32,816 - £40,322 per annum

Fixed Term - Available asap until 31 December 2021

Ref: S&E-14937

Applications are invited for a Postdoctoral Research Associate to work with Professor Jason Micklefield at the Manchester Institute of Biotechnology (MIB, ?url=http%3A%2F%2Fwww.mib.ac.uk&module=jobs&id=177527" target="_blank" rel="nofollow">www.mib.ac.uk ), for two years starting from January 2020. The project is funded by the Royal Society International Collaboration Awards and will involve collaboration with Professor Roberto Berlinck, Universidade de Sao Paulo in Brazil.

The project aims to discover, characterise and engineer new biosynthetic pathways to next generation antibiotics that are urgently required to combat antimicrobial resistance (AMR) and to treat neglected tropical diseases (NTD) in the developing world. We will focus on pathways to nonribosomal peptide and polyketide natural products. New approaches will be developed for engineering nonribosomal peptide synthetase (NRPS), polyketide synthase (PKS) and tailoring enzymes to create antibiotic assembly lines in Streptomyces or related bacterial hosts.

You will join a large interdisciplinary team of biologists and chemists in the MIB. Funding is also available for travel to visit collaborators in Sao Paulo, Brazil. You must hold a PhD, or have equivalent postdoctoral experience in enzymology/biochemistry and/or molecular biology/microbial genetics.

As an equal opportunities employer we welcome applicants from all sections of the community regardless of gender, ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.

Contact and Address

For further information about research in our lab see:



Enquiries about the vacancy:

  • Vacancy, shortlisting and interviews: Professor Jason Micklefield at micklefieldmanchester.ac.uk or 0161 306 4509.
  • General enquiries: hrservicesmanchester.ac.uk or 0161 275 4499.
  • Technical support: universityofmanchesterhelpmeapply.co.uk or 0161 850 2004

Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.

To apply, please click on the apply button to visit our website.

Closing date: 6 January 2020.


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In your application, please refer to myScience.uk and reference JobID 177527.

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